Evidence map›Paper›PMID 36374043›Full record

ArticlemSphere2022

Biochemical Identification of a Nuclear Coactivator Protein Required for AtrR-Dependent Gene Regulation in Aspergillus fumigatus.

Sanjoy Paul, Shivani Ror, W Hayes McDonald, W Scott Moye-Rowley

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Two ZnApplied and environmental microbiology · 2024
    Article
  5. Loss of a conserved C-terminal region of thebioRxiv : the preprint server for biology · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sanjoy PaulDepartment of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowagrid.214572.7, Iowa City, Iowa, USA.
Shivani RorDepartment of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowagrid.214572.7, Iowa City, Iowa, USA.
W Hayes McDonaldProteomics Laboratory, Mass Spectrometry Research Center, Department of Biochemistry, Vanderbilt Universitygrid.152326.1 Medical Center, Nashville, Tennessee, USA.
W Scott Moye-RowleyDepartment of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowagrid.214572.7, Iowa City, Iowa, USA.ORCID 0000-0002-7163-1120
University of Iowa · USVanderbilt University Medical Center · US

Funding

Elevated gene transcription of the cyp51A gene is essential for azole drug resistance in Aspergillus fumigatusR01AI143198 · NIAID · UNIVERSITY OF IOWA · PI W Scott Moye-Rowley · 2019 to 2026
$3.9M
Transcriptional networks governing A. fumigatus virulenceR01AI162802 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI FILLER, SCOTT G, MOYE-ROWLEY, W SCOTT · 2021 to 2025
$3.3M
NIAID NIH HHS R01 AI143198NIAID NIH HHS R01 AI162802
6 · The paper itself

Abstract

Azole drugs represent the primary means of treating infections associated with the filamentous fungal pathogen Aspergillus fumigatus. A central player in azole resistance is the Zn

Indexed as

Aspergillus fumigatusFungal ProteinsAzolesFungiHumansNuclear ProteinsTranscription FactorsAzolesFungal ProteinsNuclear ProteinsTranscription FactorsABC transportersantifungalAspergillus fumigatusazoleergosteroltranscription factors

Identifiers

PMID36374043
PMCPMC9769526
OpenAlexW4308953343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.