Evidence map›Paper›PMID 36373844›Full record

ArticleAmerican journal of medical genetics. Part A2023

Anxiety in Wiedemann-Steiner syndrome.

Rowena Ng, Hans Tomas Bjornsson, Jill A Fahrner, Jacqueline Harris

Open access · greenAbstract read
In one paragraph

Article in American journal of medical genetics. Part A, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Revisiting Wiedemann-Steiner Syndrome: NovelBalkan medical journal · 2026
    Article
  2. Review
  3. Article
  4. Associations Between Executive Functioning, Behavioral Functioning, and Adaptive Functioning Difficulties in Wiedemann-Steiner Syndrome.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2024
    Article
  5. Variants inGenes · 2024
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Rowena NgKennedy Krieger Institute, Baltimore, Maryland, USA.ORCID 0000-0001-7193-4300
Hans Tomas BjornssonDepartment of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Jill A FahrnerDepartment of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Jacqueline HarrisKennedy Krieger Institute, Baltimore, Maryland, USA.
Kennedy Krieger Institute · USJohns Hopkins University · USReykjavík University · IS

Funding

QAQC Johns Hopkins Institute for Clinical and Translational ResearchUL1TR003098 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2019 to 2023
$57.7M
Sleep and Circadian Dysfunction, Brain and Neurobehavioral Development in AutismP50HD103538 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI Stewart H Mostofsky · 2020 to 2026
$9.9M
Exploring Disrupted H3K27me3 in Mendelian Disorders of the Epigenetic Machinery and Restoring Its Balance as a Therapeutic Approach to Treat Abnormal GrowthK08HD086250 · NICHD · JOHNS HOPKINS UNIVERSITY · PI FAHRNER, JILL A · 2018 to 2023
$966k
Preparing for a Clinical Trial in Kabuki Syndrome- Characterization of Cognitive and Neuroanatomical Features and Pilot Treatment TrialK23HD101646 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI HARRIS, JACQUELINE · 2020 to 2024
$843k
NCATS NIH HHS UL1 TR003098NICHD NIH HHS K08 HD086250NICHD NIH HHS K23 HD101646NICHD NIH HHS P50 HD103538
6 · The paper itself

Abstract

This study examined anxiety in Wiedemann-Steiner syndrome (WSS). Eighteen caregivers and participants with WSS completed the parent- and self-report versions of the Screen for Child Anxiety Related Disorder or the adapted version of the Screen for Adult Anxiety Related Disorder. Approximately 33.33% of parents and 65% of participants with WSS rated in the clinical range for overall anxiety. Across anxiety subtypes, parents primarily indicated concerns with Separation Anxiety (72%), which was also endorsed by the majority of participants with WSS (82%). The emergent trend showed Total Anxiety increased with age based on parent-informant ratings. The behavioral phenotype of WSS includes elevated anxiety. Clinical management should include incorporating early behavioral interventions to bolster emotion regulation given the observed risk of anxiety with age.

Indexed as

Abnormalities, MultipleIntellectual DisabilityAnxietyContractureCraniofacial AbnormalitiesFaciesGrowth DisordersHumansHypertrichosisMicrocephalyanxietydevelopmental psychopathologygenetics/genetic disordersKMT2Amental health

Identifiers

PMID36373844
PMCPMC9907226
OpenAlexW4308956340

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.