Evidence map›Paper›PMID 36373403›Full record

Trial reportThe American journal of clinical nutrition2022

Physical activity and individual plasma phospholipid SFAs in pregnancy: a longitudinal study in a multiracial/multiethnic cohort in the United States.

Xinyue Liu, Liwei Chen, Zhe Fei, Sifang K Zhao, Yeyi Zhu, Tong Xia, Jin Dai, Mohammad L Rahman, Jing Wu, Natalie L Weir and 2 more

Registry-linked trialOpen access · greenAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The American journal of clinical nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00912132 (The National Standard for Normal Fetal Growth), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00912132 completednot on this map

The National Standard for Normal Fetal Growth

TypeobservationalSponsorEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Ran2009 to 2013Enrolled2,802ConditionsPregnancy, Fetal Growth
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Xinyue LiuDepartment of Epidemiology, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA, USA.
Liwei ChenDepartment of Epidemiology, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-8458-5661
Zhe FeiDepartment of Biostatistics, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA, USA.ORCID 0000-0001-9568-2857
Sifang K ZhaoEpidemiology Branch, Division of Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA.ORCID 0000-0002-9019-2186
Yeyi ZhuDivision of Research, Kaiser Permanente Northern California, Oakland, CA, USA.ORCID 0000-0002-7296-738X
Tong XiaDepartment of Epidemiology, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA, USA.
Jin DaiDepartment of Epidemiology, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA, USA.
Mohammad L RahmanDivision of Cancer Epidemiology & Genetics, National Cancer Institute, NIH, Bethesda, MD, USA.ORCID 0000-0001-8322-0495
Jing WuEpidemiology Branch, Division of Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA.
Natalie L WeirDepartment of Laboratory Medicine & Pathology, University of Minnesota, Minneapolis, MN, USA.
Michael Y TsaiDepartment of Laboratory Medicine & Pathology, University of Minnesota, Minneapolis, MN, USA.ORCID 0000-0001-7553-3408
Cuilin ZhangEpidemiology Branch, Division of Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA.ORCID 0000-0002-8014-2708
University of California, Los Angeles · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USUniversity of Minnesota · USKaiser Permanente · USNational Cancer Institute · USNational University of Singapore · SG

Funding

Reducing disparities in birth outcomes: a randomized controlled trial on CenteringPregnancyR01HD082311 · NICHD · CLEMSON UNIVERSITY · PI CROCKETT, AMY HAIRSTON, HEO, MOONSEONG · 2015 to 2019
$2.7M
Fetal Programming of Growth and Obesity: A Metabolomics ApproachK01DK120807 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI ZHU, YEYI · 2019 to 2022
$699k
CDC HHS T42 OH008412NICHD NIH HHS HHSN275200800002INICHD NIH HHS HHSN275200800012CNICHD NIH HHS HHSN275200800013CNICHD NIH HHS HHSN275200800014CNICHD NIH HHS HHSN275200800028CNICHD NIH HHS HHSN275201000001ZNICHD NIH HHS HHSN275201000009CNICHD NIH HHS R01 HD082311NIDDK NIH HHS K01 DK120807NIDDK NIH HHS K01DK120807NIOSH CDC HHS T42 OH008412
6 · The paper itself

Abstract

backgroundCirculating individual SFAs in pregnant females are critical for maternal and fetal health. However, research on identifying their modifiable factors is limited.

objectivesWe aimed to examine the associations of total physical activity (PA) and types of PA with circulating individual SFAs during pregnancy in a multiracial/multiethnic cohort of pregnant females in the United States.

methodsThe study included participants in a nested case-control study (n = 321) from the Eunice Kennedy Shriver NICHD Fetal Growth Studies-Singleton Cohort. Sampling weights were applied, so the results represented the entire Fetal Growth Cohort. Plasma phospholipid SFAs were measured at 4 visits [10-14 (visit 1), 15-26 (visit 2), 23-31 (visit 3), and 33-39 (visit 4) weeks of gestation] throughout pregnancy. PA of the previous year at visit 1 and since the previous visit at the subsequent visits was assessed using the validated Pregnancy PA Questionnaire. Time-specific and longitudinal associations were examined using multivariable linear and generalized estimating equation models.

resultsTotal PA (metabolic equivalent of task-h/wk) was positively associated with circulating heptadecanoic acid (17:0) at visit 1 (β × 103: 0.07; 95% CI: 0.02, 0.11) and pentadecanoic acid (15:0) at visit 3 (β × 103: 0.09; 95% CI: 0.03, 0.14) independent of sociodemographic, reproductive, pregnancy, and dietary factors. Across the 4 visits, the positive associations with total PA were consistent for pentadecanoic acid (β × 103: 0.06; 95% CI: 0.02, 0.10) and heptadecanoic acid (β × 103: 0.10; 95% CI: 0.06, 0.14). Out of the 4 PA types (i.e., sports/exercise, household/caregiving, transportation, and occupational PA) considered, the magnitude of positive associations was the largest for sports/exercise PA.

conclusionsOur findings suggest that maternal PA is positively associated with circulating pentadecanoic and heptadecanoic acids. The findings warrant confirmation by future studies.This trial was registered at clinicaltrials.gov as NCT00912132.

Indexed as

ExercisePhospholipidsFemaleHumansLongitudinal StudiesPregnancyProspective StudiesUnited StatesPhospholipidsmaternal exercisePAphysical activitypregnancy healthpregnant femalesprospective cohortsaturated fatty acidsSFAs

Identifiers

PMID36373403
PMCPMC9761740
OpenAlexW4308952535

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.