Evidence map›Paper›PMID 36373005›Full record

ArticleJournal of animal science2022

Gastrointestinal dynamics, immune response, and nutrient digestibility of weanling pigs fed diets supplemented with enzymatically treated yeast1.

Emmanuel O Alagbe, Ayodeji S Aderibigbe, Hagen Schulze, Kolapo M Ajuwon, Olayiwola Adeola

Open access · greenAbstract readRandomized Controlled Trial, Veterinary
In one paragraph

Article in Journal of animal science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Emmanuel O AlagbeDepartment of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0002-0747-2866
Ayodeji S AderibigbeDivision of Agriculture Science, College of Agriculture and Food Sciences, Florida A&M University, Tallahassee, FL 32307, USA.
Hagen SchulzeLivalta, AB Agri Ltd, 64 Innovation Way, Lynchwood, Peterborough, PE2 6FL, UK.
Kolapo M AjuwonDepartment of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0002-5523-7457
Olayiwola AdeolaDepartment of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0003-2737-7679
Purdue University West Lafayette · USAB Agri · GBFlorida Agricultural and Mechanical University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this trial was to investigate the effect of enzymatically treated yeast (ETY) on the growth performance, nutrient digestibility, immune response, and gut health of weanling pigs. A total of 192 weanling pigs (6.0 ± 1.04 kg) were allocated to 4 corn and soybean-based diets with increasing concentrations of ETY (0, 1, 2, or 4 g/kg) for a 43-d trial. There were 8 replicate pens (4 replicate pens per sex) and 6 pigs per replicate. The experiment was set up as a randomized complete block design with body weight used as a blocking factor. Pigs had ad libitum access to water and diets for the duration of the study. There was no effect of ETY supplementation on the growth performance indices of weanling pigs. At day 14, there was a quadratic decrease (P < 0.05) in the apparent total tract digestibility (ATTD) of acid detergent fiber (ADF). At day 28, there was a linear increase (P < 0.05) in the ATTD of neutral detergent fiber and a quadratic decrease (P < 0.05) in the ATTD of ADF. On day 14, there was a linear increase (P < 0.05) in serum catalase activity with ETY supplementation. There was a linear increase (P < 0.01) in the gene expression of glutathione peroxidase-4 in the ileal mucosa of pigs. Increasing dietary ETY supplementation linearly decreased (P < 0.05) the gene expression of ileal peptide transporter 1. There was a tendency for a quadratic effect (P = 0.07) in the ileal villus height to crypt depth ratio with ETY supplementation. In addition, there was a tendency for a linear increase (P = 0.06) in ileal digesta butyrate with ETY supplementation. In conclusion, the current study demonstrated that dietary ETY supplementation could partly ameliorate the deleterious effects of post-weaning stress by enhancing the antioxidative status of weanling pigs. However, prolonged supplementation of ETY may be needed to see its effect on growth performance.

Indexed as

DetergentsDietary SupplementsAnimal FeedAnimal Nutritional Physiological PhenomenaAnimalsDietDigestionImmunityNutrientsSaccharomyces cerevisiaeSwineDetergentsNutrientsantioxidationbutyrateintestinal healthpostbioticsweanling pigsyeast

Identifiers

PMID36373005
PMCPMC9762883
OpenAlexW4308959573

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.