Evidence map›Paper›PMID 36372669›Full record

ArticleVaccine2022

Association between COVID-19 vaccination status, time elapsed since the last vaccine dose, morbidity, and absenteeism among healthcare personnel: A prospective, multicenter study.

Helena C Maltezou, Maria N Gamaletsou, Dimitra-Maria Koukou, Theodoros V Giannouchos, Flora Sourri, Natalia Syrimi, Amalia Karapanou, Nikolaos Lemonakis, Emmanuela Peskelidou, Konstantina Papanastasiou and 5 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Vaccine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. First Responders Have Lower COVID-19 Vaccination Rates Than Other Healthcare Providers.Journal of the American College of Emergency Physicians open · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 2 countries.

Helena C MaltezouDirectorate of Research, Studies and Documentation, National Public Health Organization, Athens, Greece. Electronic address: maltezou.helena@gmail.com.
Maria N GamaletsouPathophysiology Department, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Dimitra-Maria KoukouFirst Department of Pediatrics, University of Athens, Aghia Sophia Children's Hospital, Athens, Greece.
Theodoros V GiannouchosDepartment of Health Services Policy and Management, Arnold School of Public Health, University of South Carolina, Columbia, SC, United States.
Flora SourriDepartment of Infection Control, 251 Hellenic Air Force General Hospital, Athens, Greece.
Natalia SyrimiDepartment of Infection Control, 251 Hellenic Air Force General Hospital, Athens, Greece; Paediatric Department, 251 Air Force General Hospital, Athens, Greece.
Amalia KarapanouInfection Control Committee, Laiko General Hospital, Athens, Greece.
Nikolaos LemonakisInfection Control Committee, University Hospital of Alexandroupolis, Alexandroupolis, Greece.
Emmanuela PeskelidouCOVID-19 Intensive Care Unit, 424 General Military Hospital of Thessaloniki, Thessaloniki, Greece.
Konstantina PapanastasiouOperating Rooms, 424 General Military Hospital of Thessaloniki, Thessaloniki, Greece.
Periklis PanagopoulosSecond Department of Internal Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.
Kyriakos SouliotisFaculty of Social and Political Sciences, University of Peloponnese, Corinth, Greece; Health Policy Institute, Athens, Greece.
Athanasia LouridaInfection Control Committee, Aghia Sofia Children's Hospital, Athens, Greece.
Dimitrios HatzigeorgiouMedical Directorate, Hellenic National Defence General Staff, Athens, Greece.
Nikolaos V SipsasPathophysiology Department, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Hellenic Air Force · GRNational and Kapodistrian University of Athens · GR424 General Military Hospital · GRDemocritus University of Thrace · GRIaso Children’s Hospital · GRLaiko General Hospital of Athens · GRNational Public Health Organization · GRUniversity Hospital of Alexandroupolis · GRUniversity of Peloponnese · GRUniversity of South Carolina · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimWe assessed the impact of COVID-19 vaccination status and time elapsed since the last vaccine dose on morbidity and absenteeism among healthcare personnel (HCP) in the context of a mandatory vaccination policy.

methodsWe followed 7592 HCP from November 15, 2021 through April 17, 2022. Full COVID-19 vaccination was defined as a primary vaccination series plus a booster dose at least six months later.

resultsThere were 6496 (85.6 %) fully vaccinated, 953 (12.5 %) not fully vaccinated, and 143 (1.9 %) unvaccinated HCP. A total of 2182 absenteeism episodes occurred. Of 2088 absenteeism episodes among vaccinated HCP with known vaccination status, 1971 (94.4 %) concerned fully vaccinated and 117 (5.6 %) not fully vaccinated. Fully vaccinated HCP had 1.6 fewer days of absence compared to those not fully vaccinated (8.1 versus 9.7; p-value < 0.001). Multivariable regression analyses showed that full vaccination was associated with shorter absenteeism compared to not full vaccination (OR: 0.56; 95 % CI: 0.36-0.87; p-value = 0.01). Compared to a history of ≤ 17.1 weeks since the last dose, a history of > 17.1 weeks since the last dose was associated with longer absenteeism (OR: 1.22, 95 % CI:1.02-1.46; p-value = 0.026) and increased risk for febrile episode (OR: 1.33; 95 % CI: 1.09-1.63; p-value = 0.004), influenza-like illness (OR: 1.53, 95 % CI: 1.02-2.30; p-value = 0.038), and COVID-19 (OR: 1.72; 95 % CI: 1.24-2.39; p-value = 0.001).

conclusionsThe COVID-19 pandemic continues to impose a considerable impact on HCP. The administration of a vaccine dose in less than four months before significantly protected against COVID-19 and absenteeism duration, irrespective of COVID-19 vaccination status. Defining the optimal timing of boosters is imperative.

Indexed as

COVID-19Influenza, HumanInfluenza VaccinesAbsenteeismCOVID-19 VaccinesDelivery of Health CareHealth PersonnelHumansMorbidityPandemicsProspective StudiesVaccinationCOVID-19 VaccinesInfluenza VaccinesAbsenteeismBoosterCOVID-19 vaccinationHealthcare personnelMorbidity

Identifiers

PMID36372669
PMCPMC9597548
OpenAlexW4307567544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.