Evidence map›Paper›PMID 36372281›Full record

GuidelineAnnals of oncology : official journal of the European Society for Medical Oncology2023

Biliary tract cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.

A Vogel, J Bridgewater, J Edeline, R K Kelley, H J Klümpen, D Malka, J N Primrose, L Rimassa, A Stenzinger, J W Valle and 2 more

3 registry-linked trialsAbstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in Annals of oncology : official journal of the European Society for Medical Oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 418 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
418citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07176962 recruitingnot on this map

A Cell-free DNA Methylation Liquid Biopsy for Diagnosis and Management of Biliary Tract Cancers

TypeobservationalSponsorYingbin Liu, MD, PhD, FACSRan2020 to 2026Enrolled1,800ConditionsGall Bladder Cancer, Intrahepatic Cholangiocarcinoma (Icc), Extrahepatic Cholangiocarcinoma, Hilar Cholangiocarcinoma
NCT07325877 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Supra-papillary Versus Trans-papillary Biliary Stenting in Malignant Peri-hilar Stenosis (SupraBilS): a Randomized Controlled Trial

TypeinterventionalSponsorAzienda Ospedaliera Universitaria Integrata VeronaRan2026 to 2029Enrolled70ConditionsBiliary Disease Tract, Biliary Stenosis, Biliary StentsArmsERCP with suprapapillary stent placement, ERCP with transpapillary stent placement
NCT07635290 phase2active not recruitingnot on this mapstarted 2026, after this paper: background citation

A Phase II Clinical Trial of Anlotinib Combined With Cadonilimab and PULSAR in Previously Treated Advanced Unresectable or Metastatic Biliary Tract Cancer

TypeinterventionalSponsorWest China HospitalRan2026 to 2028Enrolled26ConditionsPreviously Treated, Advanced, Biliary Tract CancersArmsAnlotinib + Cadonilimab, PULSAR
3 · Its place in the literature

Who cites it

418 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Radiological Loco-Regional Treatments for Cholangiocarcinoma: A Systematic Review of the Literature.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. SEOM-GEMCAD-TTD clinical guidelines for biliary tract cancer (2025).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Guideline
  7. Trial
  8. Trial
  9. Erdafitinib in Patients with FGFR-Altered Advanced or Metastatic Cholangiocarcinoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2026
    Trial
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Sunitinib as Second-Line Treatment in Advanced Intrahepatic Cholangiocarcinoma: Results From the SUN-CK GERCOR Phase II Trial.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Trial
  15. Trial
  16. Observational
  17. Article
  18. Review
  19. Article
  20. Article

358 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

A VogelDepartment of Gastroenterology, Hepatology and Endocrinology, Medical School of Hannover, Hannover, Germany.
J BridgewaterCancer Institute, University College London (UCL), London, UK.
J EdelineDepartment of Medical Oncology, CLCC Eugène Marquis, Rennes, France; Chemistry, Oncogenesis, Stress and Signaling (COSS), INSERM, University of Rennes, Rennes, France.
R K KelleyHelen Diller Family Comprehensive Cancer Center, University of California, San Francisco, USA.
H J KlümpenDepartment of Medical Oncology, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.
D MalkaDepartment of Medical Oncology, Institut Mutualiste Montsouris, Paris, France; INSERM U1279, Université Paris-Saclay, Villejuif, France.
J N PrimroseUniversity Department of Surgery, University Hospital Southampton, Southampton, UK.
L RimassaDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy; Medical Oncology and Hematology Unit, Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.
A StenzingerInstitute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
J W ValleDivision of Cancer Sciences, University of Manchester, Manchester, UK; Department of Medical Oncology, The Christie NHS Foundation Trust, Manchester, UK.
M DucreuxINSERM U1279, Université Paris-Saclay, Villejuif, France; Department of Cancer Medicine, Gustave Roussy, Villejuif, France.
ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org

Funding

Cancer Research UK 4273
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bile Duct NeoplasmsBiliary Tract NeoplasmsCholangiocarcinomaGallbladder NeoplasmsBile Ducts, IntrahepaticFollow-Up StudiesHumanscholangiocarcinomadiagnosisfollow-upgallbladder cancerprecision medicinetreatment

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.