ArticleNeurobiology of aging2023
Depressive symptoms are associated with reduced positivity preferences in episodic memory in aging.
Article in Neurobiology of aging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Mapping the evolution of neurofeedback research: a bibliometric analysis of trends and future directions.Frontiers in human neuroscience · 2024Pooled it
- Longitudinal associations and mechanisms linking frailty, depression, and self-perceptions of aging among community-dwelling older adults: a psychosomatic interaction perspective.Frontiers in public health · 2026Article
- Further unpacking age-related differences in mind wandering: The roles of emotional valence and meta-awareness.Memory & cognition · 2025Article
- Evidence of the age-related positivity bias in autobiographical memories of the 2020 United States Presidential election outcome.Memory (Hove, England) · 2025Article
- Age exacerbates the negative effect of depression on executive functioning in racial and ethnic minorities.Brain imaging and behavior · 2024Article
- More organized white matter is associated with positivity bias in older adults.Brain imaging and behavior · 2024Article
- Age exacerbates the negative effect of depression on executive functioning in racial and ethnic minorities.Research square · 2023Article
- Resting-state functional connectivity of the cerebellum-cerebrum in older women with depressive symptoms.BMC psychiatry · 2023Article
- Age-related reductions in arousal-enhanced memory are moderated by trait emotion regulation.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Age-related positivity preferences are represented as greater memory benefits for positive and/or reduced benefits for negative material with age. It is unknown if positivity preferences are limited to older adults without depressive symptoms. In this fMRI study, adults across the lifespan with a range of depressive symptoms were scanned as they rated emotional intensity of images and subsequently completed a recognition memory task. Behavioral, univariate, and functional connectivity analyses provided evidence for interactive effects between age and depressive symptoms. With low depressive symptoms, typical age-related emotional preferences emerged: younger age was associated with better memory for negative images, and this benefit was reduced with older age. With increasing depressive symptoms in older age, positivity preferences were reduced, manifesting as improvements in negative memory. The neural data highlighted potential underlying mechanisms, including reductions in prefrontal cortex connectivity reflecting diminished ability to engage regulatory processes to reduce negative affect in older participants with higher depressive symptoms. These findings suggest that depressive symptoms in older adulthood reduce positivity preferences through alterations in neural networks underlying emotion regulation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.