Evidence map›Paper›PMID 36371750›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2023

"Visualization" of pain using cerebral

Christian Christensen Støttrup, Caius Holst Mortensen, Reza Piri, Mohsen Khosravi, Andrew Newberg, Mikkel Østerheden Andersen, Abass Alavi, Peter Grupe, Poul Flemming Høilund-Carlsen

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In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Christian Christensen StøttrupCenter for Spine Surgery and Research, Lillebaelt Hospital, Middelfart, Denmark.
Caius Holst MortensenDepartment of Nuclear Medicine, Odense University Hospital, Odense, Denmark.
Reza PiriDepartment of Nuclear Medicine, Odense University Hospital, Odense, Denmark.
Mohsen KhosraviDepartment of Radiology, Thomas Jefferson University, Philadelphia, PA, USA.
Andrew NewbergDepartment of Radiology, Marcus Institute of Integrative Health, Thomas Jefferson University, Philadelphia, PA, USA.
Mikkel Østerheden AndersenCenter for Spine Surgery and Research, Lillebaelt Hospital, Middelfart, Denmark.
Abass AlaviDepartment of Radiology, Thomas Jefferson University, Philadelphia, PA, USA.
Peter GrupeDepartment of Nuclear Medicine, Odense University Hospital, Odense, Denmark.
Poul Flemming Høilund-CarlsenDepartment of Nuclear Medicine, Odense University Hospital, Odense, Denmark. pfhc@rsyd.dk.ORCID 0000-0001-7420-2367
University of Southern Denmark · DKThomas Jefferson University · USOdense University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe hypothesized that unilateral leg pain following surgical treatment of lumbar disc herniation (LDH) is associated with an increase in the glucose metabolism of the contralateral thalamus.

methodsPatients scheduled for surgery due to LDH underwent

resultsTwenty-six patients (ten females) aged 49.7 ± 7.4 (mean ± SD) years were included. There was a significant correlation between painful body side and increased contralateral thalamic uptake of FDG, with regard to cSUVmean values. Correlation analyses including clinical parameters and cSUVmean indicated some association with 1-year change in EQ-5D.

conclusionThese preliminary data sustain the hypothesis that unilateral pain in patients with LDH is associated with increased glucose metabolism in the contralateral thalamus, suggesting a central role of thalamus in chronic pain perception.

Indexed as

Chronic PainIntervertebral Disc DisplacementFemaleFluorodeoxyglucose F18GlucoseHumansLumbar VertebraePositron Emission Tomography Computed TomographyQuality of LifeTreatment OutcomeFluorodeoxyglucose F18Glucose18F-FDGLumbar disc herniationPainPain perceptionPETQuantificationThalamus

Identifiers

PMID36371750
OpenAlexW4308891840

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.