Evidence map›Paper›PMID 36371699›Full record

ArticleJournal of clinical and experimental neuropsychology2022

Preoperative cognition predicts clinical stroke/TIA and mortality after surgical aortic valve replacement in older adults.

Stephanie M Simone, Catherine C Price, Thomas F Floyd, Molly Fanning, Steven R Messé, Deborah A G Drabick, Tania Giovannetti, Determining Neurologic Outcomes from Valve Operations (DENOVO) Investigators

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical and experimental neuropsychology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Role of Cognitive Frailty in Older Adults With Cardiovascular Disease.Journal of the American Heart Association · 2024
    Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Stephanie M SimoneDepartment of Psychology and Neuroscience, Temple University, Philadelphia, PA, USA.
Catherine C PriceDepartment of Clinical and Health Psychology, University of Florida College of Medicine, Gainesville, FL, USA.
Thomas F FloydDepartment of Anesthesiology and Pain Management, University of Texas Southwestern, Dallas, TX, USA.
Molly FanningDepartment of Surgery, University of Pennsylvania, Philadelphia, PA, USA.
Steven R MesséDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, USA.
Deborah A G DrabickDepartment of Psychology and Neuroscience, Temple University, Philadelphia, PA, USA.
Tania GiovannettiDepartment of Psychology and Neuroscience, Temple University, Philadelphia, PA, USA.ORCID 0000-0001-5661-152X
Determining Neurologic Outcomes from Valve Operations (DENOVO) Investigators
Temple University · USUniversity of Pennsylvania · USThe University of Texas Southwestern Medical Center · USUniversity of Florida · US

Funding

Stroke & cognition in surgical aortic stenosisR01HL084375 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI ACKER, MICHAEL ANDREW · 2007 to 2011
$3.8M
Assessing Everyday Function in Older Adults with the Virtual KitchenR01AG062503 · NIA · TEMPLE UNIV OF THE COMMONWEALTH · PI GIOVANNETTI, TANIA · 2020 to 2024
$1.8M
Perioperative Cognitive Anesthesia Network (PeCAN) Program for Alzheimer’s Disease and Related DementiasK07AG066813 · NIA · UNIVERSITY OF FLORIDA · PI PRICE, CATHERINE E · 2020 to 2024
$810k
Improving Everyday Task Performance through Repeated Practice in Virtual RealityR21AG066771 · NIA · TEMPLE UNIV OF THE COMMONWEALTH · PI GIOVANNETTI, TANIA · 2020 to 2021
$438k
Feasibility of the SmartPrompt for Improving Everyday Function in DementiaR21AG060422 · NIA · TEMPLE UNIV OF THE COMMONWEALTH · PI GIOVANNETTI, TANIA · 2019 to 2020
$426k
NHLBI NIH HHS R01 HL084375NIA NIH HHS K07 AG066813NIA NIH HHS R01 AG062503NIA NIH HHS R21 AG060422NIA NIH HHS R21 AG066771
6 · The paper itself

Abstract

Stroke and death remain risks of surgical aortic valve replacement (SAVR). Preoperative cognitive screeners repeatedly show that reduced scores predict postoperative outcome, but less is known about comprehensive neuropsychological measures predicting risk. This study had two aims: 1) investigate whether preoperative cognitive measures predicted postoperative clinical stroke/transient ischemic attack (TIA) and mortality in older adults undergoing SAVR, and 2) identify the best predictors within a comprehensive cognitive protocol. A total of 165 participants aged 65 + with moderate-to-severe aortic stenosis completed a comprehensive cognitive test battery preoperatively. Postoperative stroke evaluations were conducted by trained stroke neurologists preoperatively and postoperatively, and mortality outcomes were obtained by report and records. Logistic regressions were conducted to evaluate preoperative cognitive predictors of clinical stroke/TIA within 1 week of surgery and mortality within 1 year of surgery. Multivariate models showed measures of delayed verbal memory recall (OR = 0.86; 95% CI 0.74-0.99) and visuospatial skills (OR = 0.95; 95% CI 0.90-1.01) predicted clinical stroke/TIA within 1 week of surgery,

Indexed as

Ischemic Attack, TransientStrokeAgedAortic ValveCognitionHumansRisk FactorsTreatment Outcomeaortic valve replacementAortic valve stenosiscognitionmortalityneuropsychologystroke

Identifiers

PMID36371699
PMCPMC9923940
OpenAlexW4308890921

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.