Evidence map›Paper›PMID 36371665›Full record

ArticleHeart (British Cardiac Society)2023

Selection of patients for mechanical circulatory support for refractory out-of-hospital cardiac arrest.

Louise Linde, Sivagowry Rasalingam Mørk, Emilie Gregers, Jo Bønding Andreasen, Jens Flensted Lassen, Hanne Berg Ravn, Henrik Schmidt, Lars Peter Riber, Sisse Anette Thomassen, Helle Laugesen and 9 more

Open access · bronzeAbstract read
In one paragraph

Article in Heart (British Cardiac Society), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Intra-arrest blood-based biomarkers for out-of-hospital cardiac arrest: A scoping review.Journal of the American College of Emergency Physicians open · 2024
    Article
  4. Article
  5. Is Extracorporeal Membrane Oxygenation a Panacea?The Eurasian journal of medicine · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 1 country.

Louise LindeDepartment of Cardiology, Odense University Hospital, Odense, Denmark.ORCID 0000-0002-7757-2571
Sivagowry Rasalingam MørkDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
Emilie GregersDepartment of Cardiology, Copenhagen University Hospital Rigshospitalet, Kobenhavn, Denmark.
Jo Bønding AndreasenDepartment of Anesthesiology and Intensive Care, Aalborg University Hospital, Aalborg, Denmark.
Jens Flensted LassenDepartment of Cardiology, Odense University Hospital, Odense, Denmark.
Hanne Berg RavnDepartment of Anesthesiology and Intensive Care, Odense University Hospital, Odense, Denmark.
Henrik SchmidtDepartment of Anesthesiology and Intensive Care, Odense University Hospital, Odense, Denmark.
Lars Peter RiberDepartment of Cardiothoracic and Vascular Surgery, Odense University Hospital, Odense, Denmark.
Sisse Anette ThomassenDepartment of Anesthesiology and Intensive Care, Aalborg University Hospital, Aalborg, Denmark.
Helle LaugesenDepartment of Anesthesiology and Intensive Care, Aalborg University Hospital, Aalborg, Denmark.
Hans EiskjærDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
Christian Juhl TerkelsenDepartment of Cardiology B, Aarhus University Hospital, Aarhus, Denmark.
Steffen ChristensenDepartment of Anesthesiology and Intensive Care, Aarhus University Hospital, Aarhus, Denmark.
Mariann TangDepartment of Thoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, Denmark.
Hasse Moeller-SoerensenDepartment Clinical Medicine, Copenhagen University, Kobenhavn, Denmark.
Lene HolmvangDepartment of Cardiology, Copenhagen University Hospital Rigshospitalet, Kobenhavn, Denmark.
Jesper KjaergaardDepartment of Cardiology, Copenhagen University Hospital Rigshospitalet, Kobenhavn, Denmark.
Christian HassagerDepartment of Cardiology, Copenhagen University Hospital Rigshospitalet, Kobenhavn, Denmark.
Jacob Eifer MollerDepartment of Cardiology, Odense University Hospital, Odense, Denmark jacob.moeller1@rsyd.dk.ORCID 0000-0003-2873-5845
Odense University Hospital · DKAarhus University Hospital · DKCopenhagen University Hospital · DKAalborg University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe characteristics of patients admitted with refractory cardiac arrest for possible extracorporeal cardiopulmonary resuscitation (ECPR) and gain insight into the reasons for refraining from treatment in some.

methodsNationwide retrospective cohort study involving all tertiary centres providing ECPR in Denmark. Consecutive patients admitted with ongoing chest compression for evaluation for ECPR treatment were enrolled. Presenting characteristics, duration of no-flow and low-flow time, end-tidal carbon dioxide (ETCO

resultsOf 579 patients admitted with refractory cardiac arrest for possible ECPR, 221 patients (38%) proceeded to ECPR and 358 patients (62%) were not considered candidates. Median prehospital low-flow time was 70 min (IQR 56 to 85) in ECPR patients and 62 min (48 to 81) in no-ECPR patients, p<0.001. Intra-arrest transport was more than 50 km in 92 (42%) ECPR patients and 135 in no-ECPR patients (38%), p=0.25. The leading causes for not initiating ECPR stated by the treating team were duration of low-flow time in 39%, severe metabolic derangement in 35%, and in 31% low ETCO

conclusionsIn this large nationwide study of patients admitted for possible ECPR, two-thirds of patients were not treated with ECPR. The most frequent reasons to abstain from ECPR were long duration of prehospital low-flow time, metabolic derangement and low ETCO

Indexed as

Cardiopulmonary ResuscitationExtracorporeal Membrane OxygenationOut-of-Hospital Cardiac ArrestHumansPatient SelectionRetrospective StudiesEMERGENCY MEDICINEEthics, MedicalHeart-Assist Devices

Identifiers

PMID36371665
PMCPMC9872231
OpenAlexW4297850865

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.