Evidence map›Paper›PMID 36371618›Full record

SynthesisPsycho-oncology2023

Proxy ratings of psychological well-being in patients with primary brain tumors: A systematic review.

Timothy S Sannes, Miryam Yusufov, Hermioni L Amonoo, Elizabeth G Broden, Darcy E Burgers, Paul Bain, Cristina Pozo-Kaderman, Damien M Miran, Timothy S Smith, Ilana M Braun and 1 more

Abstract readSystematic Review
In one paragraph

Synthesis in Psycho-oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Proxy reporting in health: a scoping review of instructions, perspectives, and reporting experiences.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Timothy S SannesDivision of Adult Psychosocial Oncology and Palliative Care, Dana Farber Cancer Institute, Boston, Massachusetts, USA.ORCID 0000-0003-4479-0350
Miryam YusufovDivision of Adult Psychosocial Oncology and Palliative Care, Dana Farber Cancer Institute, Boston, Massachusetts, USA.ORCID 0000-0002-0254-3864
Hermioni L AmonooDivision of Adult Psychosocial Oncology and Palliative Care, Dana Farber Cancer Institute, Boston, Massachusetts, USA.
Elizabeth G BrodenDivision of Adult Psychosocial Oncology and Palliative Care, Dana Farber Cancer Institute, Boston, Massachusetts, USA.
Darcy E BurgersDivision of Adult Psychosocial Oncology and Palliative Care, Dana Farber Cancer Institute, Boston, Massachusetts, USA.
Paul BainCountway Library, Harvard Medical School, Boston, Massachusetts, USA.
Cristina Pozo-KadermanDivision of Adult Psychosocial Oncology and Palliative Care, Dana Farber Cancer Institute, Boston, Massachusetts, USA.
Damien M MiranDivision of Adult Psychosocial Oncology and Palliative Care, Dana Farber Cancer Institute, Boston, Massachusetts, USA.
Timothy S SmithHarvard Medical School, Boston, Massachusetts, USA.
Ilana M BraunDivision of Adult Psychosocial Oncology and Palliative Care, Dana Farber Cancer Institute, Boston, Massachusetts, USA.
William F PirlDivision of Adult Psychosocial Oncology and Palliative Care, Dana Farber Cancer Institute, Boston, Massachusetts, USA.ORCID 0000-0001-5226-9886

Funding

A Positive Psychology Intervention for Allogeneic Stem Cell Transplant Patients.K08CA251654 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI AMONOO, HERMIONI L. · 2020 to 2024
$1.3M
A Novel Intervention for Avoidance-Related Opioid Misuse in Patients with CancerK08CA259538 · NCI · DANA-FARBER CANCER INST · PI Miryam Yusufov · 2022 to 2026
$787k
NCI NIH HHS K08 CA251654NCI NIH HHS K08 CA259538
6 · The paper itself

Abstract

objectiveThis systematic review examined the agreement of proxy ratings of depression and anxiety in neuro-oncology patients.

methodsSearches were conducted across 4 databases (MEDLINE, Embase, PsycINFO, CINAHL, and Web of Science) to identify studies that compared proxy ratings (non-health care providers) of anxiety and depression in patients with brain cancer. Methodological quality and potential risk of bias were evaluated using the Joanna Briggs Institute Critical Appraisal Checklist.

resultsOut of the 936 studies that were screened for inclusion, 6 were included for review. The findings were mixed in terms of whether patient and proxy ratings were accurate (e.g., deemed equivalent), with many of the selected studies suggesting moderate level of agreement for several of the selected studies and, when both depression and anxiety were included, depression ratings from proxy raters were more accurate than for anxiety. We identified important limitations across the selected articles, such as low sample size, clarity on defining proxy raters and the different instructions that proxy raters are given when asked to assess patients' mood symptoms.

conclusionsOur findings suggest that proxy ratings of depression and anxiety should be interpreted with caution. While there is some agreement in proxy and patients with brain cancer ratings of depression and anxiety (greater agreement for depression), future work should recruit larger samples, while also remaining mindful of defining proxy raters and the instructions given in collecting these ratings.

Indexed as

Brain NeoplasmsPsychological Well-BeingAffectAnxietyHealth PersonnelHumansProxyanxietycancercaregiverdepressionneuro-oncologyoncologyproxy ratingsscreening

Identifiers

PMID36371618
PMCPMC10373343

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.