ReviewPrenatal diagnosis2022
Fetal cerebral ventriculomegaly: What do we tell the prospective parents?
Review in Prenatal diagnosis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Molecular Diagnostic Yield of Exome Sequencing in Patients With Congenital Hydrocephalus: A Systematic Review and Meta-Analysis.JAMA network open · 2023Pooled it
- The Role of Fetal MRI in the Evaluation of Ventriculomegaly: A Scoping Review.Children (Basel, Switzerland) · 2026Review
- Dangling Choroid Plexus: An Early Sign of Fetal Anomaly.Diagnostics (Basel, Switzerland) · 2026Article
- Therapeutic Termination of Pregnancy Under the Umbrella of Environmental, Socio-Economic Factors and High-Risk Pregnancy.Diagnostics (Basel, Switzerland) · 2026Review
- Clinical characteristics and outcome of fetuses with ventriculomegaly: a retrospective multicenter study.Archives of gynecology and obstetrics · 2026Article
- Novel histone deacetylase 6 gene variant is associated with fetal hydrocephalus and lateral ventriculomegaly.American journal of translational research · 2026Article
- Computational Study of Tesla Valve Design for Vesico-Amniotic Shunt to Manage Lower Urinary Tract Obstruction and Pleural Effusion.Bioengineering (Basel, Switzerland) · 2025Article
- First Trimester Ultrasound Soft Markers in a Fetus: Genetic Associations and Diagnostic Implications.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2025Review
- Open Spinal Dysraphism Without Hindbrain Herniation-Natural History and Postnatal Outcome.Prenatal diagnosis · 2025Article
- Genetic etiology of ventriculomegaly in 73 fetuses identified by High-Throughput sequencing.Scientific reports · 2025Article
- Cavum Septi Pellucidi et Vergae in the Pathogenesis of Prenatally Detected Ventriculomegaly.Current medical imaging · 2025Article
- Expert consensus on fetal ventriculomegaly: evidence-based recommendations for 23 key clinical questions.Frontiers in pediatrics · 2025Article
- Current Diagnostic, Counseling, and Treatment Options in Non-Severe and Severe Apparently Isolated Fetal Ventriculomegaly.Biomedicines · 2024Review
- Clinical characteristics and perinatal outcome of fetuses with ventriculomegaly.Archives of gynecology and obstetrics · 2024Article
- Clinical characteristics and perinatal outcome of fetuses with ventriculomegaly.Archives of gynecology and obstetrics · 2024Article
- Isolated Fetal Ventriculomegaly: Diagnosis and Treatment in the Prenatal Period.Children (Basel, Switzerland) · 2024Review
- Prenatal diagnosis and pregnancy outcomes in fetuses with ventriculomegaly.Frontiers in medicine · 2024Article
- Chromosomal Abnormalities Detected by Chromosomal Microarray Analysis and Karyotype in Fetuses with Ultrasound Abnormalities.International journal of general medicine · 2024Article
- White matter changes in fetal brains with ventriculomegaly.Frontiers in neuroanatomy · 2023Article
- Fetal cerebral ventriculomegaly: What do we tell the prospective parents?Prenatal diagnosis · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Fetal cerebral ventriculomegaly is a relatively common finding, observed during approximately 1% of obstetric ultrasounds. In the second and third trimester, mild (≥10 mm) and severe ventriculomegaly (≥15 mm) are defined according to the measurement of distal lateral ventricles that is included in the routine sonographic examination of central nervous system. A detailed neurosonography and anatomy ultrasound should be performed to detect other associated anomalies in the central nervous system and in other systems, respectively. Fetal MRI might be useful when neurosonography is unavailable or suboptimal. The risk of chromosomal and non-chromosomal genetic disorders associated with ventriculomegaly is high, therefore invasive genetic testing, including microarray, is recommended. Screening for prenatal infections, in particular cytomegalovirus and toxoplasmosis, should also be carried out at diagnosis. The prognosis is determined by the severity of ventriculomegaly and/or by the presence of co-existing abnormalities. Fetal ventriculoamniotic shunting in progressive isolated severe ventriculomegaly is an experimental procedure. After delivery, ventricular-peritoneal shunting or ventriculostomy are the two available options to treat hydrocephalus in specific conditions with similar long-term outcomes. A multidisciplinary fetal neurology team, including perinatologists, geneticists, pediatric neurologists, neuroradiologists and neurosurgeons, can provide parents with the most thorough prenatal counseling. This review outlines the latest evidence on diagnosis and management of pregnancies complicated by fetal cerebral ventriculomegaly.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.