Evidence map›Paper›PMID 36371203›Full record

ArticleAnnals of clinical microbiology and antimicrobials2022

Hidden in plain sight: urinary Cryptococcus neoformans missed by routine diagnostics in a patient with acute leukemia.

Zoe F Weiss, James E DiCarlo, David W Basta, Stephanie Kent, Alexis Liakos, Lindsey Baden, Manfred Brigl, Sanjat Kanjilal, Connie Cañete-Gibas, Nathan P Wiederhold and 1 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of clinical microbiology and antimicrobials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Haematologic and Urologic Manifestations ofCase reports in infectious diseases · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Zoe F WeissDepartment of Pathology, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, USA. zoefreemanweiss@gmail.com.
James E DiCarloDepartment of Pathology, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, USA.
David W BastaDepartment of Pathology, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, USA.
Stephanie KentDepartment of Pathology, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, USA.
Alexis LiakosDivision of Infectious Diseases, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, USA.
Lindsey BadenDivision of Infectious Diseases, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, USA.
Manfred BriglDepartment of Pathology, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, USA.
Sanjat KanjilalDivision of Infectious Diseases, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, USA.
Connie Cañete-GibasFungus Testing Laboratory, Department of Pathology and Laboratory Medicine, Long School of Medicine, University of Texas Health San Antonio, Texas, USA.
Nathan P WiederholdFungus Testing Laboratory, Department of Pathology and Laboratory Medicine, Long School of Medicine, University of Texas Health San Antonio, Texas, USA.
Sankha S BasuDepartment of Pathology, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, USA.
Brigham and Women's Hospital · USHarvard University · USHarvard Pilgrim Health Care · USThe University of Texas at San Antonio · USThe University of Texas Health Science Center at San Antonio · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryptococcuria is a rare manifestation of localized cryptococcal disease. We present a case of Cryptococcus neoformans urinary tract infection in an immunocompromised host missed by routine laboratory workup. The patient had negative blood cultures, a negative serum cryptococcal antigen (CrAg), and "non-Candida yeast" growing in urine culture that was initially dismissed as non-pathogenic. The diagnosis was ultimately made by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) from a repeat urine culture after transfer to a tertiary care center. Cryptococcus should be considered in the differential of refractory urinary tract infections growing non-Candida yeast.

Indexed as

CryptococcosisCryptococcus neoformansLeukemiaUrinary Tract InfectionsCandidaHumansSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationCryptoccouriaCryptococcal antigenCryptococcal infectionCryptococcus neoformansIndia-inkMALDI-TOF MS

Identifiers

PMID36371203
PMCPMC9655867
OpenAlexW4309072433

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.