Evidence map›Paper›PMID 36370352›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Analysis of CCN Functions in Liver Regeneration After Partial Hepatectomy.

Naiyuan Cheng, Ki-Hyun Kim, Lester F Lau

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Naiyuan ChengDepartment of Biochemistry and Molecular Genetics, University of Illinois at Chicago, College of Medicine, Chicago, IL, USA.
Ki-Hyun Kim
Lester F LauDepartment of Biochemistry and Molecular Genetics, University of Illinois at Chicago, College of Medicine, Chicago, IL, USA. LFLau@uic.edu.

Funding

Regulation of TNF-alpha by Integrin-Mediated Matrix SignalingR01GM078492 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LAU, LESTER F · 2007 to 2018
$4.3M
The Matricellular Protein CCN1 in Wound HealingR01AR061791 · NIAMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LAU, LESTER F · 2011 to 2021
$3.8M
Integrin-mediated matricellular signaling in experimental colitisR01DK108994 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LAU, LESTER F · 2017 to 2020
$1.7M
NIAMS NIH HHS R01 AR061791NIDDK NIH HHS R01 DK108994NIGMS NIH HHS R01 GM078492
6 · The paper itself

Abstract

The remarkable regenerative capability of the liver has long been appreciated. Upon significant loss of liver tissue, the remnant liver can grow rapidly to restore the original liver mass through a combination of hepatocyte proliferation and hypertrophy to maintain homeostasis. Experimentally, 2/3 partial hepatectomy in mice has been used extensively as a model to dissect the molecular mechanism of liver regeneration and the genetic networks involved. Herein, we describe the protocols for partial hepatectomy and analyses of pertinent CCN protein functions.

Indexed as

HepatectomyLiver RegenerationAnimalsCell ProliferationHepatocytesHyperplasiaLiverMiceLiverPartial hepatectomyProliferationRegenerationSenescenceSurgery

Identifiers

PMID36370352

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.