Evidence map›Paper›PMID 36370340›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Optimal CCN4 Immunofluorescence for Tissue Microarray.

Pierre-Olivier Gaudreau, Isabelle Cousineau, John Stagg

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 68% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Pierre-Olivier GaudreauDepartment of Oncology, Queen's University and Canadian Cancer Trials Group, Kingston, ON, Canada. p-ogaudreau@ctg.queensu.ca.
Isabelle CousineauCentre de recherche du Centre hospitalier de l'Université de Montréal, Institut du Cancer de Montréal, Montréal, QC, Canada.
John StaggCentre de recherche du Centre hospitalier de l'Université de Montréal, Institut du Cancer de Montréal, Montréal, QC, Canada.
Centre Hospitalier de l’Université de Montréal · CAQueen's University · CA

Funding

STRUCTURE AND BONE MATRIX GENE EXPRESSIONZ01DE000379 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI YOUNG, MARIAN F · 1985 to 2008
$2.5M
CIHR 364476Intramural NIH HHS Z01 DE000379
6 · The paper itself

Abstract

CCN4 (also known as WNT1-Inducible Signaling Pathway Protein 1 or WISP1) is a 367 amino acid, 40 kDa protein located on chromosome 8q24.1-8q24.3. Prior studies have provided support for a pro-inflammatory role for CCN4. We have shown recently that CCN4 expression is associated with advanced disease, epithelial-mesenchymal transition, and an inflamed tumor microenvironment in multiple solid tumors. We detail here the CCN4 tissue microarray immunofluorescence protocol related to these findings.

Indexed as

CCN Intercellular Signaling ProteinsNeoplasmsEpithelial-Mesenchymal TransitionFluorescent Antibody TechniqueHumansTumor MicroenvironmentCCN Intercellular Signaling ProteinsCCN4CCN proteinsIFImmunofluorescenceTissue microarrayTMAWISP1

Identifiers

PMID36370340
OpenAlexW4309082069

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.