Evidence map›Paper›PMID 36370126›Full record

ReviewClinical and experimental immunology2022

B cells in human lymphoid structures.

Lucia Montorsi, Jacqueline H Y Siu, Jo Spencer

Open access · hybridAbstract readReview
In one paragraph

Review in Clinical and experimental immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Eutopic Endometrium Immune Changes Involved in Development and Progression of Endometriosis: A Review.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. B cells defined by immunoglobulin isotypes.Clinical and experimental immunology · 2022
    Article
  9. Human B cells.Clinical and experimental immunology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lucia MontorsiPeter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK.
Jacqueline H Y SiuPeter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK.ORCID 0000-0001-5181-407X
Jo SpencerPeter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK.ORCID 0000-0002-7202-2431
King's College London · GB

Funding

Wellcome Trust 220872/Z/20/Z
6 · The paper itself

Abstract

Most B cells in the human body are present in tissues where they support immune responses to pathogens, vaccines, autoantigens, and tumours. Despite their clear importance, they are very difficult to study and there are many areas of uncertainty that are difficult to resolve because of limited tissue access. In this review, we consider the zonal structure of lymphoid tissues, the B cell subsets they contain, and how these are regulated. We also discuss the impact that methods of deep interrogation have made on our current knowledge base, especially with respect to studies of cells from dissociated tissues. We discuss in some detail the controversial B cells with marginal zone distribution that some consider being archived memory B cells. We anticipate that more we understand of B cells in tissues and the niches they create, the more opportunities will be identified to harness their potential for therapeutic benefit.

Indexed as

B-LymphocytesB-Lymphocyte SubsetsAutoantigensHumansLymphoid TissueAutoantigensB cellshumanlymphoid tissues

Identifiers

PMID36370126
PMCPMC9985168
OpenAlexW4308826698

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.