Evidence map›Paper›PMID 36369829›Full record

ReviewHuman vaccines & immunotherapeutics2022

The employment of vaccinia virus for colorectal cancer treatment: A review of preclinical and clinical studies.

Qiaoyun Ling, Bichun Zheng, Xudong Chen, Shaoshun Ye, Quan Cheng

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Human vaccines & immunotherapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Qiaoyun LingDepartment of Anorectal Surgery, The Affiliated People's Hospital of Ningbo University, Ningbo, China.
Bichun ZhengDepartment of Anorectal Surgery, The Affiliated People's Hospital of Ningbo University, Ningbo, China.
Xudong ChenDepartment of Anorectal Surgery, The Affiliated People's Hospital of Ningbo University, Ningbo, China.
Shaoshun YeDepartment of Anorectal Surgery, The Affiliated People's Hospital of Ningbo University, Ningbo, China.
Quan ChengDepartment of Anorectal Surgery, The Affiliated People's Hospital of Ningbo University, Ningbo, China.
Ningbo University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is one of the leading malignancies that causes death worldwide. Cancer vaccines and oncolytic immunotherapy bring new hope for patients with advanced CRC. The capability of vaccinia virus (VV) in carrying foreign genes as antigens or immunostimulatory factors has been demonstrated in animal models. VV of Wyeth, Western Reserve, Lister, Tian Tan, and Copenhagen strains have been engineered for the induction of antitumor response in multiple cancers. This paper summarized the preclinical and clinical application and development of VV serving as cancer vaccines and oncolytic vectors in CRC treatment. Additionally, the remaining challenges and future direction are also discussed.

Indexed as

Cancer VaccinesColorectal NeoplasmsOncolytic VirotherapyOncolytic VirusesAnimalsImmunotherapyVaccinia virusCancer Vaccinescancer vaccineclinicalcolorectal canceroncolytic immunotherapypreclinicalVaccinia virus

Identifiers

PMID36369829
PMCPMC9746450
OpenAlexW4308834431

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.