Evidence map›Paper›PMID 36369813›Full record

ArticleThe journal of the Royal College of Physicians of Edinburgh2022

Performance status: A key factor in predicting mortality in the first wave of COVID-19 in South-East Scotland.

Callum P Mutch, Daniella A Ross, Anda Bularga, Roo Nicola Rose Cave, Margo E Chase-Topping, Atul Anand, Nicholas L Mills, Oliver Koch, Claire L Mackintosh, Meghan R Perry and 1 more

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Article in The journal of the Royal College of Physicians of Edinburgh, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Callum P MutchClinical Infection Research Group, NHS Lothian Infection Service, Western General Hospital, Edinburgh, EH4 2JP, UK.
Daniella A RossClinical Infection Research Group, NHS Lothian Infection Service, Western General Hospital, Edinburgh, EH4 2JP, UK.
Anda BulargaBHF Centre for Cardiovascular Sciences, University of Edinburgh, Edinburgh, UK.
Roo Nicola Rose CaveEpidemiology Research Group, Usher Institute, University of Edinburgh, Edinburgh, UK.
Margo E Chase-ToppingEpidemiology Research Group, Usher Institute, University of Edinburgh, Edinburgh, UK.
Atul AnandBHF Centre for Cardiovascular Sciences, University of Edinburgh, Edinburgh, UK.
Nicholas L MillsBHF Centre for Cardiovascular Sciences, University of Edinburgh, Edinburgh, UK.
Oliver KochClinical Infection Research Group, NHS Lothian Infection Service, Western General Hospital, Edinburgh, EH4 2JP, UK.
Claire L MackintoshClinical Infection Research Group, NHS Lothian Infection Service, Western General Hospital, Edinburgh, EH4 2JP, UK.
Meghan R PerryClinical Infection Research Group, NHS Lothian Infection Service, Western General Hospital, Edinburgh, EH4 2JP, UK.
DataLoch COVID-19 Collaborative

Funding

British Heart Foundation RE/18/5/34216Medical Research Council MR/V007254/1
6 · The paper itself

Abstract

backgroundCOVID-19 mortality risk factors have been established in large cohort studies; long-term mortality outcomes are less documented.

methodsWe performed multivariable logistic regression to identify factors associated with in-patient mortality and intensive care unit (ICU) admission in symptomatic COVID-19 patients admitted to hospitals in South-East Scotland from 1st March to 30th June 2020. One-year mortality was reviewed.

resultsOf 726 patients (median age 72; interquartile range: 58-83 years, 55% male), 104 (14%) required ICU admission and 199 (27%) died in hospital. A further 64 died between discharge and 30th June 2021 (36% overall 1-year mortality). Stepwise logistic regression identified age >79 (odds ratio (OR), 4.77 (95% confidence interval (CI), 1.96-12.75)), male sex (OR, 1.83 (95% CI, 1.21-2.80)) and higher European Cooperative Oncology Group/World Health Organization performance status as associated with higher mortality risk. DISCUSSION: Poor functional baseline was the predominant independent risk factor for mortality in COVID-19. More than one-third of individuals had died by 1 year following admission.

Indexed as

COVID-19AgedFemaleHospitalizationHospital MortalityHumansIntensive Care UnitsMaleRetrospective StudiesRisk FactorsSARS-CoV-2clinical scoresCOVID-19frailtymortalitySARS-CoV2

Identifiers

PMID36369813
PMCPMC9659484

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.