Observational studyAnnals of medicine2022
Adverse events: an expensive and avoidable hospital problem.
Observational study in Annals of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Objective technical skills assessment in laparoscopic cholecystectomy: a systematic review of manual, kinematic, and AI-based tools.Surgical endoscopy · 2026Pooled it
- Factors of the Nursing Practice Environment Shaping Nurses' Perceived Benefits of Adverse Event Reporting: A Cross-Sectional Study Among Primary Healthcare Nurses.Healthcare (Basel, Switzerland) · 2026Article
- Risk factors associated with nursing-sensitive adverse events in older hospitalised patients: A retrospective chart review.International journal of nursing studies advances · 2026Article
- Article
- Global burden of adverse effects of medical treatment from 1990 to 2021: a Global Burden of Disease Study 2021.The Korean journal of internal medicine · 2026Article
- Association Between Workplace Gaslighting and Perceived Quality of Care, Patient Safety and Quiet Quitting: A Cross-Sectional Study Among Nurses in Greece.Healthcare (Basel, Switzerland) · 2026Article
- Exploring the knowledge gaps and reporting procedures for adverse events among professional nurses: evidence from Mopani district, Limpopo province, South Africa.Frontiers in health services · 2026Article
- Impact of patient safety on hospital prognosis: Association between adverse events and in-hospital mortalit.Clinical medicine (London, England) · 2026Observational
- Exploring Medication Errors with Antipsychotics in Saudi Arabia: Insights from a Nationwide Analysis.Healthcare (Basel, Switzerland) · 2025Article
- Use of Failure Mode and Effect Analysis Methods in Pediatric and Adolescent Hospital Care: A Scoping Review.Journal of patient safety · 2025Article
- Impact of second victim experience and support and psychological empowerment on depressive symptoms among nurses in China -a latent class analysis.BMC psychology · 2025Article
- Assessment of the occurrence of adverse events through the global trigger tool in a university hospital in Italy.Scientific reports · 2025Article
- Anxiety and Depression and Related Risk Factors in Italian Healthcare Providers Involved in Adverse Events.Healthcare (Basel, Switzerland) · 2025Article
- [Levels of prevention of non-clinical adverse events in a health unit].Revista medica del Instituto Mexicano del Seguro Social · 2025Article
- Interprofessional education interventions for healthcare professionals to improve patient safety: a scoping review.Medical education online · 2024Article
- Leveraging Open-Source Large Language Models for Data Augmentation in Hospital Staff Surveys: Mixed Methods Study.JMIR medical education · 2024Article
- Validation in the Greek Language of the Patients' Perception of the Surgical Safety Questionnaire.Cureus · 2024Article
- Psychometric evaluation of the Vietnamese version of nurses' ethical behaviors for protecting patient rights scale (V-NEBPPRS): a methodological study.BMC nursing · 2024Article
- Adverse events during the COVID-19 pandemic in Ecuador: high frequency of healthcare-associated infections and increasing hospital stay and costs.Infection prevention in practice · 2023Article
- Inappropriate hospital admission as a risk factor for the subsequent development of adverse events: a cross-sectional study.BMC medicine · 2023Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAdverse healthcare-related events (AE) entail reduced patient safety. Estimating their frequency, characteristics, avoidability and impact is a means to identify targets for improvement in the quality of care.
methodsThis was a descriptive observational study conducted within the Patient Safety Incident Study in Hospitals in the Community of Madrid (ESHMAD). The study was conducted in a high-complexity hospital in May 2019 through a two-phase electronic medical record review: (1) AE screening and epidemiological and clinical data collection and (2) AE review and classification and analysis of their impact, avoidability, and associated costs.
resultsA total of 636 patients were studied. The prevalence of AE was 12.4%. Death during the stay was associated with the presence of AE (OR [CI95%]: 2.15 [1.07 to 4.52]) versus absence and emergency admission (OR [CI95%]: 17.11[6.63 to 46.26]) versus scheduled. A total of 70.2% of the AEs were avoidable. Avoidable AEs were associated with the presence of pressure ulcers (OR [CI95%]: 2.77 [1.39 to 5.51]), central venous catheter (OR [CI95%]: 2.58 [1.33 to 5.00]) and impaired mobility (OR [CI95%]: 2.24[1.35 to 3.71]), versus absences. They were associated too with the stays in the intensive care unit (OR [CI95%]: 2.75 [1.07 to 7.06]) versus medical service. AEs were responsible for additional costs of €909,716.8 for extra days of stay and €12,461.9 per patient with AE.
conclusionsThe prevalence of AEs was similar to that found in other studies. AEs led to worse patient outcomes and were associated with the patient's death. Although avoidable AEs were less severe, their higher frequency produced a greater impact on the patient and healthcare system.Key messagesAdverse events are one of the main problems in healthcare delivery and patients who suffer from at least one AE are double as likely to die during hospitalization.Avoidable adverse events are the most frequent in health care and they are a good target where achieve improvement areas that allow getting optimal patient safety and quality of care levels.Patients hospitalized in the ICU, with the previous presence of pressure ulcers, central venous catheter, or impaired mobility were associated with the development of avoidable AE, so optimal management of these patients would reduce the impact of AE.
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