Evidence map›Paper›PMID 36369625›Full record

ArticleHormones (Athens, Greece)2023

Influence of fasting plasma glucose-lowering rate on BNP levels in type 2 diabetes mellitus patients with coronary microcirculation dysfunction.

Ziying Zhang, Yangwen Chen, Qian Wang, Lingli Xie, Yongyan Shan, Ning Yang, Weihua Wu

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Article in Hormones (Athens, Greece), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ziying ZhangDepartment of Endocrinology, The Third Affiliated Hospital of Shenzhen University, Shenzhen, 518000, People's Republic of China.
Yangwen ChenThe First Affiliated Hospital of Harbin Medical University, Harbin, 150001, People's Republic of China.
Qian WangThe First Affiliated Hospital of Harbin Medical University, Harbin, 150001, People's Republic of China.
Lingli XieDepartment of Endocrinology, The Third Affiliated Hospital of Shenzhen University, Shenzhen, 518000, People's Republic of China.
Yongyan ShanThe First Affiliated Hospital of Harbin Medical University, Harbin, 150001, People's Republic of China.
Ning Yang *The First Affiliated Hospital of Harbin Medical University, Harbin, 150001, People's Republic of China. huakaixx2020@126.com.
Weihua Wu *Department of Endocrinology, The Third Affiliated Hospital of Shenzhen University, Shenzhen, 518000, People's Republic of China. wwhnfmk@163.com.ORCID http://orcid.org/0000-0002-3173-0183

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim was to analyze the influence of fasting plasma glucose-lowering rate (FPGLR) on plasma BNP levels in type 2 diabetes mellitus (T2DM) patients with coronary microcirculation dysfunction (CMD) and to determine the optimal FPGLR for these patients.

methodsA total of 170 T2DM patients who received intensive glucose-lowering therapy during hospitalization in the First Affiliated Hospital of Harbin Medical University were enrolled. Ninety-two patients with CMD and 78 patients without CMD were assigned to a study and a control group, respectively. The study group was stratified as S1 (4.1 ~ 6.0 mmol·L

resultsIn the study and the control group, the BNP level in S1 was significantly higher than that in C1 (87 vs. 12 pg/ml, P < 0.001), although there was no significant difference between S2 and C2, S3 and C3. In the study group, the BNP level in S1 was significantly higher than that in S2 (87 vs. 22 pg/ml, P < 0.001) and S3 (87 vs. 15 pg/ml, P < 0.001), but there was no significant difference between S2 and S3.

conclusionRapid intensive glucose-lowering may lead to increased plasma BNP levels in T2DM patients with CMD. Optimal FPGLR for these patients was determined to be no more than 4.0 mmol·L

Indexed as

Diabetes Mellitus, Type 2Blood GlucoseFastingHumansMicrocirculationBlood GlucoseBrain natriuretic peptide levelsCoronary microcirculation dysfunctionGlucose-lowering rateType 2 diabetes mellitus

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.