Evidence map›Paper›PMID 36369483›Full record

ArticleLeukemia2022

Not only mutations but also tumorigenesis can be substantially attributed to DNA damage from reactive oxygen species in RUNX1::RUNX1T1-fusion-positive acute myeloid leukemia.

Jeffrey D Mandell, J Nick Fisk, Ethan Cyrenne, Mina L Xu, Vincent L Cannataro, Jeffrey P Townsend

Open access · hybridAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jeffrey D MandellProgram in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0002-3839-2543
J Nick FiskProgram in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0002-1940-393X
Ethan CyrenneDepartment of Biostatistics, Yale School of Public Health, New Haven, CT, USA.
Mina L XuDepartment of Pathology, Yale School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0001-9513-245X
Vincent L CannataroDepartment of Biology, Emmanuel College, Boston, MA, USA.ORCID http://orcid.org/0000-0002-6364-7747
Jeffrey P TownsendProgram in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA. Jeffrey.Townsend@Yale.edu.ORCID http://orcid.org/0000-0002-9890-3907
Yale University · USEmmanuel College - Massachusetts · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Core Binding Factor Alpha 2 SubunitLeukemia, Myeloid, AcuteCarcinogenesisDNA DamageHumansMutationOncogene Proteins, FusionReactive Oxygen SpeciesRUNX1 Translocation Partner 1 ProteinTranslocation, GeneticCore Binding Factor Alpha 2 SubunitOncogene Proteins, FusionReactive Oxygen SpeciesRUNX1 protein, humanRUNX1T1 protein, humanRUNX1 Translocation Partner 1 Protein

Identifiers

PMID36369483
PMCPMC9712081
OpenAlexW4308834902

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.