Evidence map›Paper›PMID 36369335›Full record

ReviewCommunications biology2022

Progress and gaps of extracellular vesicle-mediated intercellular cargo transfer in the central nervous system.

Chun Wan, Michael H B Stowell, Jingshi Shen

Abstract readReview
In one paragraph

Review in Communications biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Extracellular RNAs as Messengers and Early Biomarkers in Neurodegeneration.International journal of molecular sciences · 2025
    Review
  2. Article
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  5. Article
  6. Review
  7. Article
  8. Article
  9. Providing anFrontiers in microbiology · 2024
    Article
  10. Article
  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chun WanDepartment of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO, 80309, USA.
Michael H B StowellDepartment of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO, 80309, USA.ORCID 0000-0001-7250-1419
Jingshi ShenDepartment of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO, 80309, USA. jingshi.shen@colorado.edu.ORCID 0000-0001-9595-1148

Funding

Protein-membrane interactions in regulated exocytosisR35GM126960 · NIGMS · UNIVERSITY OF COLORADO · PI Jingshi Shen · 2018 to 2026
$3.2M
Identifying exosome-mediated cargo transport machinery in Alzheimer's diseaseRF1AG061829 · NIA · UNIVERSITY OF COLORADO · PI SHEN, JINGSHI, STOWELL, MICHAEL H. B. · 2018 to 2018
$2.7M
NIA NIH HHS RF1 AG061829NIGMS NIH HHS R35 GM126960U.S. Department of Health & Human Services | National Institutes of Health (NIH) AG061829
6 · The paper itself

Abstract

A fundamentally novel function proposed for extracellular vesicles (EVs) is to transfer bioactive molecules in intercellular signaling. In this minireview, we discuss recent progress on EV-mediated cargo transfer in the central nervous system (CNS) and major gaps in previous studies. We also suggest a set of experiments necessary for bridging the gaps and establishing the physiological roles of EV-mediated cargo transfer.

Indexed as

Extracellular VesiclesCell CommunicationCentral Nervous System

Identifiers

PMID36369335
PMCPMC9652383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.