ArticleThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation2023
Heart waitlist survival in adults with an intra-aortic balloon pump relative to other Status 2, Status 1, and inotrope Status 3 patients.
Article in The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Low rates of inotropic support and durable left ventricular assist device placement among status 2 heart transplant candidates with temporary mechanical circulatory support.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2026Article
- A systematic review and meta-analysis of axillary intra-aortic balloon pump as a bridge to advanced heart failure therapy.Frontiers in cardiovascular medicine · 2026Review
- Impact of the United Network for Organ Sharing allocation criteria changes on temporary mechanical circulatory support use as a bridge to transplant.World journal of transplantation · 2025Review
- Policy and Oversight of Cardiac Transplantation.Methodist DeBakey cardiovascular journal · 2025Review
- A Milestone in Cardiac Care: The Intra-Aortic Balloon Pump in Cardiac Surgery and Transplantation.Brazilian journal of cardiovascular surgery · 2024Article
- Bridging Over Troubled Waters-How the United States 2018 Heart Allocation System Altered Transplant Bridging Strategies.Reviews in cardiovascular medicine · 2024Review
- An explainable machine learning approach using contemporary UNOS data to identify patients who fail to bridge to heart transplantation.Frontiers in cardiovascular medicine · 2024Article
- Association of high-priority exceptions with waitlist mortality among heart transplant candidates.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2023Article
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Authors and funding
10 authors.
Funding
Abstract
backgroundIntra-aortic balloon pump (IABP) utilization has significantly outpaced other Status 2 eligibility criteria for heart transplant. The risk of waitlist mortality of IABP-supported patients relative to other Status 2 listed patients has not been described.
methodsWe performed a retrospective analysis of all adult patients listed Status 2 for heart transplantation under the current U.S. allocation policy, using data from the United Network for Organ Sharing. Patients listed status 1 and status 3 for high-dose inotropes were included for reference. Mortality and waitlist decompensation were modeled as a function of time-varying status in cause-specific Cox survival models.
resultsWe identified 3638 Status 2 listings, of whom 1676 (46%) were Status 2 due to IABP. Relative to patients supported with IABP, status 2 patients with ventricular tachycardia/fibrillation [VT/VF] (HR 4.0, p < .001), right-or-biventricular assist device configurations (HR 2.3, p = .002), or temporary surgical left ventricular assist devices [LVAD] (HR 2.6, p = .003) had greater risk of waitlist mortality and decompensation. Other Status 2 subgroups had mortality comparable to IABP Status 2. Risk of waitlist mortality and decompensation for IABP Status 2 was similar to Status 3 patients listed for high-dose inotropes (HR 1.2, p = .27) and lower than Status 1 patients (HR 0.7, p = .002).
conclusionsWaitlist mortality varies significantly by Status 2 eligibility criteria and is highest among patients listed for VT/VF, right-or-biVAD configurations, or temporary surgical LVADs. IABP-supported patients were among those with the lowest Status 2 waitlist mortality risk and comparable to Status 3 inotrope-supported patients.
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