Observational studyBMC musculoskeletal disorders2022
Chronic low back pain: a prospective study with 4 to 15 years follow-up after a multidisciplinary biopsychosocial rehabilitation program.
Observational study in BMC musculoskeletal disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Evolution of Outcome Assessment in Chronic Low Back Pain Clinical Trials Throughout the 20th and 21st Centuries: A Scoping Review.Musculoskeletal care · 2026Article
- Pain in People Living With Obesity: Baseline Multidimensional Profiles, Prevalence and Biopsychosocial Factors From a Cohort Study.European journal of pain (London, England) · 2026Article
- Study on the effect of aquatic exercise combined with hot spring bathing for patients with chronic low back pain: a randomized controlled trial.BMC sports science, medicine & rehabilitation · 2026Article
- Five-Year Follow-Up of Patients with Persistent Painful Temporomandibular Disorder After Multidisciplinary Assessment.Journal of pain research · 2026Article
- Economic burden of recurrent low back pain among working-age adults in Poland: a 3-year retrospective observational analysis.Frontiers in public health · 2026Observational
- Pain Phenotyping Indicators in Older Adults with Chronic Low Back Pain: A Secondary Analysis of a Randomized Controlled Trial.Journal of pain research · 2025Article
- Multidisciplinary rehabilitation with a focus on physiotherapy in patients with Post Covid19 condition: an observational pilot study.European archives of psychiatry and clinical neuroscience · 2024Observational
- Biopsychosocial rehabilitation in the working population with chronic low back pain: a concept analysis.Journal of rehabilitation medicine · 2024Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMultidisciplinary biopsychosocial rehabilitation (MBR) in patients with chronic low back pain (CLBP) is superior to less intensive treatments for at least one year, but the long-term course of the disease is largely unknown. The primary aim of this study was to describe the long-term course of an MBR in relation to pain, disability, and quality of life from the beginning of an MBR to between 4 to 15 years after participation. The secondary aim was to explore the long-term course of an MBR in relation to physiological outcomes of functioning.
methodsThis was a observational study conducted at a university hospital. The cohort consisted of participants of a 3-week, CLBP-specific MBR program between August 2001 and January 2013. The North American Spine Society questionnaire (NASS) pain and disability scale was the primary patient -reported outcome measure (PROM). The NASS neurogenic symptoms scale and the Short-Form 36 (SF-36) health survey were secondary PROMs. Patients were assessed before entry to the MBR (T0), at entry (T1), at discharge (T2) and 4 to 15 years after discharge (T3). Effects were quantified by effect size (ES). Score differences were tested for significance using parametric or non-parametric tests and linear mixed models.
resultsOf 299 consecutive patients from the MBR program, 229 could be contacted. Of these, 84 declined participation, five did not meet the inclusion criteria, and 26 had incomplete data. Thus, 114 patients were included. The mean follow-up time was 9.2 years. At T3, patients exhibited beneficial effects for NASS pain and disability with a moderate ES (ES = 0.63; p < 0.001). The NASS neurogenic symptoms scale was stable. The SF-36 scales showed an improvement in the bodily pain domain (ES = 1.02; p < 0.001), but no significant changes for physical functioning, physical role, general health, vitality, social functioning, emotional role, or mental health. The physical health component summary was improved (ES = 0.40, p = 0.002), and the mental health summary was unchanged. The linear mixed model analysis confirmed improvements in pain and disability between T1 and T3 (p = 0.010).
conclusionsThe results of this study suggest that there is a long-term benefit of MBR participation in patients with CLBP.
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