Evidence map›Paper›PMID 36368776›Full record

ArticleRespiratory care2023

Mechanical Ventilation in ARDS With an Automatic Resuscitator.

Mayson LA Sousa, Bhushan H Katira, Doreen Engelberts, Vanessa Hsing, Annia Schreiber, Annemijn H Jonkman, Martin Post, Paul Dorian, Laurent J Brochard

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mayson LA SousaKeenan Centre for Biomedical Research, Critical Care Department, St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada.
Bhushan H KatiraTranslational Medicine Program, Research Institute, Hospital for Sick Children. University of Toronto, Toronto, Ontario, Canada.
Doreen EngelbertsTranslational Medicine Program, Research Institute, Hospital for Sick Children. University of Toronto, Toronto, Ontario, Canada.
Vanessa HsingTranslational Medicine Program, Research Institute, Hospital for Sick Children. University of Toronto, Toronto, Ontario, Canada.
Annia SchreiberKeenan Centre for Biomedical Research, Critical Care Department, St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada.
Annemijn H JonkmanKeenan Centre for Biomedical Research, Critical Care Department, St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada.
Martin PostTranslational Medicine Program, Research Institute, Hospital for Sick Children. University of Toronto, Toronto, Ontario, Canada.
Paul DorianKeenan Centre for Biomedical Research, Division of Cardiology, St Michael's Hospital, Toronto, Ontario, Canada.
Laurent J BrochardKeenan Centre for Biomedical Research, Critical Care Department, St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada. laurent.brochard@unityhealth.to.
St. Michael's Hospital · CAHospital for Sick Children · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Oxylator is an automatic resuscitator, powered only by an oxygen cylinder with no electricity required, that could be used in acute respiratory failure in situations in which standard mechanical ventilation is not available or feasible. We aimed to assess the feasibility and safety of mechanical ventilation by using this automatic resuscitator in an animal model of ARDS.

methodsA randomized experimental study in a porcine ARDS model with 12 pigs randomized to the Oxylator group or the control group (6 per group) and ventilated for 4 h. In the Oxylator group, peak pressure was set at 20 cm H

resultsAfter lung injury, the mean ± SD respiratory system compliance and P

conclusionsShort-term mechanical ventilation by using an automatic resuscitator and a fixed pressure setting in an ARDS animal model was feasible and safe.

Indexed as

Respiration, ArtificialRespiratory Distress SyndromeAnimalsLungPositive-Pressure RespirationSwineTidal Volumeartificial respirationmechanical ventilatorsrescue ventilationrespiratory distress syndromerespiratory insufficiencyventilator-induced lung injury

Identifiers

PMID36368776
PMCPMC10171348
OpenAlexW4308835066

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.