ArticleStroke and vascular neurology2023
Aetiology of extracranial carotid free-floating thrombus in a prospective multicentre cohort.
Article in Stroke and vascular neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- The Floating Threat: A Rare Case Report of Carotid Saddle Thrombus in a Healthy Adult.Clinical practice and cases in emergency medicine · 2026Article
- Angioscopy Visualized a Residual Free-Floating Thrombus in Mild Carotid Artery Stenosis Following Acute MCA Occlusion: A Case Report.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026Article
- Article
- Many strokes from a single non-stenosing plaque: from the last event a light to the first one?Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- A vertebral artery "donut sign".Acta neurologica Belgica · 2025Article
- Rapid resolution of newly formed carotid free-floating thrombus through anticoagulation therapy.BMC neurology · 2025Article
- Endovascular management of tandem embolic stroke due to cardioembolic free-floating thrombus: a case report.Frontiers in neuroscience · 2025Article
- Definition of Carotid Artery Free Floating Thrombus: A Systematic Review and Call for Standardisation of Imaging and Nomenclature.EJVES vascular forum · 2025Review
- Carotid Floating Thrombus With Patent Foramen Ovale: An Unusual Cause of Stroke in Young.Cureus · 2024Article
- Two case descriptions of urgent carotid endarterectomy: the characteristics of thrombosis and stroke at different time points.Quantitative imaging in medicine and surgery · 2024Article
- Intraluminal carotid thrombus leading to postpartum stroke: a case study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- The Prepetrous Segment of the Internal Carotid Artery as a Neglected Site of Symptomatic Atherosclerosis: A Single-Center Series.Journal of clinical medicine · 2024Article
- Triple Stentriever "Bouquet" Deployment with Zoom 88 Large-Bore Aspiration and Walrus Balloon-Guide Catheter for the Definitive Thrombectomy of a Carotid Free-Floating Thrombus.Journal of neurological surgery reports · 2024Article
- Symptomatic Carotid Free-Floating Thrombus: About Management of 50 Cases in a Referral Neurovascular Center.Journal of clinical medicine · 2023Article
- Symptomatic free-floating thrombus in the vertebral artery: a case description.Quantitative imaging in medicine and surgery · 2023Article
- Recurrent floating common carotid artery thrombus related to COVID-19: A case report.Journal de medecine vasculaire · 2023Article
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Authors and funding
13 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCarotid free-floating thrombi (FFT) in patients with acute transient ischaemic attack (TIA)/stroke have a high risk of early recurrent stroke. Management depends on aetiology, which can include local plaque rupture, dissection, coagulopathy, malignancy and cardioembolism. Our objectives were to classify the underlying aetiology of FFT and to estimate the proportion of patients with underlying stenosis requiring revascularisation.
methodsWe prospectively enrolled consecutive patients presenting to three comprehensive stroke centres with acute TIA/stroke and ipsilateral internal carotid artery FFT. The aetiology of FFT was classified as: carotid atherosclerotic disease, carotid dissection, cardioembolism, both carotid atherosclerosis and cardioembolism, or embolic stroke of uncertain source (ESUS). Patients with carotid atherosclerosis were further subclassified as having ≥50% or <50% stenosis.
resultsWe enrolled 83 patients with confirmed FFT. Aetiological assessments revealed 66/83 (79.5%) had carotid atherosclerotic plaque, 4/83 (4.8%) had a carotid dissection, 10/83 (12%) had both atrial fibrillation and carotid atherosclerotic plaque and 3/83 (3.6%) were classified as ESUS. Of the 76 patients with atherosclerotic plaque (including those with atrial fibrillation), 40 (52.6%) had ≥50% ipsilateral stenosis.
conclusionsThe majority of symptomatic carotid artery FFT are likely caused by local plaque rupture, more than half of which are associated with moderate to severe carotid stenosis requiring revascularisation. However, a significant number of FFTs are caused by non-atherosclerotic mechanisms warranting additional investigations.
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