Evidence map›Paper›PMID 36368341›Full record

ArticlePreventive medicine2022

Racial, ethnic, and language differences in screening measures for statin therapy following a major guideline change.

Jorge Kaufmann, Miguel Marino, Jennifer A Lucas, Carlos J Rodriguez, Steffani R Bailey, Ayana K April-Sanders, Dave Boston, John Heintzman

Open access · greenAbstract read
In one paragraph

Article in Preventive medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jorge KaufmannDepartment of Family Medicine, Oregon Health & Science University, Portland, OR, USA. Electronic address: kaufmjor@ohsu.edu.
Miguel MarinoDepartment of Family Medicine, Oregon Health & Science University, Portland, OR, USA; Biostatistics Group, School of Public Health, Oregon Health & Science University - Portland State University, Portland, OR, USA.
Jennifer A LucasDepartment of Family Medicine, Oregon Health & Science University, Portland, OR, USA.
Carlos J RodriguezDepartment of Medicine, Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Steffani R BaileyDepartment of Family Medicine, Oregon Health & Science University, Portland, OR, USA.
Ayana K April-SandersDepartment of Biostatistics & Epidemiology, Rutgers School of Public Health, Piscataway, NJ, USA.
Dave BostonOCHIN, Portland, OR, USA.
John HeintzmanDepartment of Family Medicine, Oregon Health & Science University, Portland, OR, USA; OCHIN, Portland, OR, USA.
Oregon Health & Science University · USAlbert Einstein College of Medicine · USOchin · USRutgers, The State University of New Jersey · US

Funding

PAST-DUE (Prevention and Social Determinants: Disparities and Utilization in Latino Elders)R01AG056337 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI HEINTZMAN, JOHN · 2018 to 2022
$2.3M
FOCUS: Foreign Born Latinos Cardiovascular ScreeningR01MD014120 · NIMHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI HEINTZMAN, JOHN · 2020 to 2024
$2.0M
NIA NIH HHS R01 AG056337NIMHD NIH HHS R01 MD014120
6 · The paper itself

Abstract

Atherosclerotic cardiovascular disease (ASCVD) disproportionally affects racial and ethnic minority populations. Statin prescribing guidelines changed in 2013 to improve ASCVD prevention. It is unknown whether risk screening for statin eligibility differed across race and ethnicity over this guideline change. We examine racial/ethnic/language differences in screening measure prevalence for period-specific statin consideration using a retrospective cohort design and linked electronic health records from 635 community health centers in 24 U.S. states. Adults 50+ years, without known ASCVD, and ≥ 1 visit in 2009-2013 and/or 2014-2018 were included, grouped as: Asian, Latino, Black, or White further distinguished by language preference. Outcomes included screening measure prevalence for statin consideration, 2009-2013: low-density lipoprotein (LDL), 2014-2018: pooled cohort equation (PCE) components age, sex, race, systolic blood pressure, total cholesterol, high-density lipoprotein, smoking status. Among patients seen both periods, change in period-specific measure prevalence was assessed. Adjusting for sociodemographic and clinical factors, compared to English-preferring White patients, all other groups were more likely to have LDL documented (2009-2013, n = 195,061) and all PCE components documented (2014-2018, n = 344,504). Among patients seen in both periods (n = 128,621), all groups had lower odds of PCE components versus LDL documented in the measures' respective period; English-preferring Black adults experienced a greater decline compared to English-preferring White adults (OR 0.81; 95% CI: 0.72-0.91). Racial/ethnic/language disparities in documented screening measures that guide statin therapy for ASCVD prevention were unaffected by a major guideline change advising this practice. It is important to understand whether the newer guidelines have altered disparate prescribing and morbidity/mortality for this disease.

Indexed as

AtherosclerosisHydroxymethylglutaryl-CoA Reductase InhibitorsAdultEthnicityHumansLanguageMinority GroupsRetrospective StudiesHydroxymethylglutaryl-CoA Reductase InhibitorsCardiovascular diseaseDisparitiesElectronic health recordMinority healthRisk screening

Identifiers

PMID36368341
PMCPMC9703970
OpenAlexW4308560899

What OpenQuestion holds

Texttitle and abstract
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.