ArticleJournal of psychiatric research2022
Neural signal variability relates to maladaptive rumination in depression.
Article in Journal of psychiatric research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Neural correlates of peripartum depression: a systematic review, meta-analysis and comparison to major depressive disorder.Molecular psychiatry · 2025Pooled it
- Functional activity and connectivity signatures of ketamine and lamotrigine during negative emotional processing: a double-blind randomized controlled fMRI study.Translational psychiatry · 2024Trial
- The mediating effect of neuroticism on the association between brain signal variability in the prefrontal cortex and depression among healthy individuals.Brain imaging and behavior · 2026Article
- Association Between Childhood Trauma and Somatization in a Clinical Sample: The Mediating Roles of Rumination, Cognitive Reappraisal, and Expressive Suppression.Psychiatry investigation · 2026Article
- Exercise intervention for rumination: from neural mechanisms to clinical applications.Frontiers in psychology · 2026Review
- Neural Circuit Taxonomy and Precision Psychiatry in Major Depression.Advances in experimental medicine and biology · 2026Review
- Increased insular functional connectivity during repetitive negative thinking in major depression and healthy volunteers.Psychological medicine · 2025Article
- Functional brain network dynamics of brooding in depression: Insights from real-time fMRI neurofeedback.Journal of affective disorders · 2025Article
- Neural correlates of rumination in remitted depressive episodes: Brain network connectivity and topology analyses.World journal of psychiatry · 2025Article
- Functional brain network dynamics of brooding in depression: insights from real-time fMRI neurofeedback.medRxiv : the preprint server for health sciences · 2024Article
- Thalamo-cortical circuits associated with trait- and state-repetitive negative thinking in major depressive disorder.Journal of psychiatric research · 2023Article
- Transdiagnostic phenomena of psychopathology in the context of the RDoC: protocol of a multimodal cross-sectional study.BMC psychology · 2023Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Rumination is a common feature of depression and predicts the onset and maintenance of depressive episodes. Maladaptive and adaptive subtypes of rumination contribute to distinct outcomes, with brooding worsening negative mood and reflection related to fewer depression symptoms in healthy populations. Neuroimaging studies have implicated several cortical midline and lateral prefrontal brain regions in rumination. Recent research indicates that blood oxygen level-dependent (BOLD) signal variability may be a novel predictor of cognitive flexibility. However, no prior studies have investigated whether brooding and reflection are associated with distinct patterns of BOLD signal variability in depression. We collected resting-state fMRI data for 79 women with different depression histories: no history, past history, and current depression. We examined differences in BOLD signal variability (BOLD
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.