SynthesisActa anaesthesiologica Scandinavica2023
The prognostic value of elevated neutrophil-lymphocyte ratio for cardiac surgery-associated acute kidney injury: A systematic review and meta-analysis.
Synthesis in Acta anaesthesiologica Scandinavica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.
- Neutrophil-to-lymphocyte ratio as a predictor of mortality in patients with acute kidney injury: a systematic review and meta-analysis.Einstein (Sao Paulo, Brazil) · 2025Pooled it
- The prognostic value of elevated neutrophil-lymphocyte ratio for cardiac surgery-associated acute kidney injury: A systematic review and meta-analysis.Acta anaesthesiologica Scandinavica · 2023Pooled it
- Smart Cardiac ICU: Digital Integration, Predictive Analytics, and Perioperative Inflammation.Bioengineering (Basel, Switzerland) · 2026Review
- Predictive role of prognostic nutritional index and geriatric nutritional risk index for postoperative mortality risk in patients with aortic dissection: a systematic review and meta-analysis.Journal of thoracic disease · 2026Article
- Discovery of postoperative clinical states linked to cardiac surgery-associated acute kidney injury.BioData mining · 2026Article
- Association of preoperative and postoperative systemic inflammatory markers with early mortality and morbidity after CABG surgery.Journal of cardiothoracic surgery · 2026Article
- The Association Between Platelet Indices and Osteoarthritis: A Systematic Review and Meta-analysis.Clinical medicine insights. Arthritis and musculoskeletal disorders · 2026Article
- Acute kidney injury among patients aged over 80 years after percutaneous coronary intervention: a multicenter, retrospective cohort study.Renal failure · 2025Article
- Associations Between Lymphopenia and the Development/Recovery of Acute Kidney Injury Among Patients Hospitalized With Respiratory Virus Infections.Kidney medicine · 2025Article
- New Insights in Assessing AKI 3 Risk Factors and Predictors Associated with On-Pump Surgical Aortic Valve Replacement.Diagnostics (Basel, Switzerland) · 2025Article
- Machine Learning Model for Predicting Risk Factors of Prolonged Length of Hospital Stay in Patients with Aortic Dissection: a Retrospective Clinical Study.Journal of cardiovascular translational research · 2025Article
- Serologic parameters in young patients with retinal vein occlusion treated with anti-vascular endothelial growth factor.International journal of ophthalmology · 2025Article
- Development and validation of a cardiac surgery-associated acute kidney injury prediction model using the MIMIC-IV database.PloS one · 2025Article
- High neutrophil-to-lymphocyte ratio as a cost-effective marker of acute kidney injury and in-hospital mortality after cardiac surgery: a case-control study.Renal failure · 2024Article
- Association between inflammatory biomarkers and postoperative acute kidney injury after cardiac surgery in patients with preoperative renal dysfunction: a retrospective pilot analysis.Journal of cardiothoracic surgery · 2024Article
- The Role of Monocyte Distribution Width in the Early Prediction of Sepsis in Patients Undergoing Cardiovascular Surgery: A Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2024Article
- Neutrophil Percentage as a Potential Biomarker of Acute Kidney Injury Risk and Short-Term Prognosis in Patients with Acute Myocardial Infarction in the Elderly.Clinical interventions in aging · 2024Observational
- Article
- Association of preoperative neutrophil-lymphocyte ratio with acute kidney injury in patients with non-cardiac surgery: difference among surgical types.International urology and nephrology · 2023Article
- Dynamic and Individualized Prediction of Acute Kidney Injury via Longitudinal Peripheral Blood Cell Trajectories among COVID-19 Inpatients: A Multicenter Prospective Cohort Study.Kidney diseases (Basel, Switzerland)Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients undergoing cardiac surgery are at significant risk of developing postoperative acute kidney injury (AKI). Neutrophil-lymphocyte ratio (NLR) is a widely available inflammatory biomarker which may be of prognostic value in this setting.
methodsWe conducted a systematic review and meta-analysis of studies reporting associations between perioperative NLR with postoperative AKI. We searched Medline, Embase and the Cochrane Library, without language restriction, from inception to May 2022 for relevant studies. We meta-analysed the reported odds ratios (ORs) with 95% confidence intervals (CIs) for both elevated preoperative and postoperative NLR with risk of postoperative AKI and need for renal replacement therapy (RRT). We conducted a meta-regression to explore inter-study statistical heterogeneity.
resultsTwelve studies involving 10,724 participants undergoing cardiac surgery were included, with eight studies being deemed at high risk of bias using PROBAST modelling. We found statistically significant associations between elevated preoperative NLR and postoperative AKI (OR 1.45, 95% CI 1.18-1.77), as well as postoperative need for RRT (OR 2.37, 95% CI 1.50-3.72). Postoperative NLR measurements were not of prognostic significance.
conclusionsElevated preoperative NLR is a reliable inflammatory biomarker for predicting AKI following cardiac surgery.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.