ReviewAmerican journal of respiratory and critical care medicine2023
Molecular Function and Contribution of
Open access · greenAbstract readReview
In one paragraph
Review in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 36 citations in OpenAlex.
- Variant Class-Specific Phenotypes and Outcomes in Pediatric TBX4-Associated Pulmonary Hypertension.Pediatric pulmonology · 2026Article
- Genetic variants in pulmonary hypertension associated with chronic obstructive pulmonary disease.Current opinion in pulmonary medicine · 2026Review
- Excessive postnatal smooth muscle differentiation in a lung-specific model of TBX4-related pulmonary hypertension.JCI insight · 2026Article
- Rare T-box variants in adult pulmonary arterial hypertension with congenital heart disease.Journal of applied genetics · 2026Article
- Inherited TBX4 frameshifting variants predicted to escape nonsense mediated decay in two families with variable phenotypes, including lethal lung developmental disorders.Human genomics · 2026Article
- Multifaceted role of T-box transcription factor 4: From embryonic development to disease pathogenesis.Genes & diseases · 2026Review
- Postnatally induced TBX4 insufficiency confers pulmonary hypertension and impairs lung development in infant mice.Pediatric research · 2026Article
- Complex Genomic Rearrangement Involving theHuman mutation · 2026Article
- Loss ofAmerican journal of respiratory cell and molecular biology · 2025Article
- TBX4 in Pulmonary Hypertension: Linking Lung Development to Precision Therapy.American journal of respiratory cell and molecular biology · 2025Article
- SOX17 in pulmonary arterial hypertension: from development to clinical phenotype.European respiratory review : an official journal of the European Respiratory Society · 2025Review
- Why some and not others? Understanding vascular phenotypes in genetic developmental lung diseases.Current opinion in pediatrics · 2025Review
- The Glu86 Residue in TBX4 Proves Critical for Human Lung Development.American journal of medical genetics. Part A · 2025Article
- A novel frameshift TBX4 variant in a family with ischio-coxo-podo-patellar syndrome and variable severity.Genes & genomics · 2025Article
- Precision Medicine for Pulmonary Vascular Disease: The Future Is Now (2023 Grover Conference Series).Pulmonary circulation · 2025Article
- RNA-Seq and ChIP-Seq Identification of Unique and Overlapping Target Genes and Pathways Regulated by TBX4 in Human Pulmonary Fibroblasts and Pericytes.Pulmonary circulation · 2025Article
- Definition, classification and diagnosis of pulmonary hypertension.The European respiratory journal · 2024Article
- Identification and functional activity of Nik related kinase (NRK) in benign hyperplastic prostate.Journal of translational medicine · 2024Article
- Neonatal persistent pulmonary hypertension related to a novel TBX4 mutation: case report and review of the literature.Italian journal of pediatrics · 2024Review
- Lateral thinking in syndromic congenital cardiovascular disease.Disease models & mechanisms · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 14 institutions in 5 countries.
Justyna A KarolakChair and Department of Genetics and Pharmaceutical Microbiology, Poznan University of Medical Sciences, Poznan, Poland.ORCID 0000-0002-2340-4513
Carrie L WelchDepartment of Pediatrics and.
Christian MosimannSection of Developmental Biology and.
Katarzyna BzdęgaChair and Department of Genetics and Pharmaceutical Microbiology, Poznan University of Medical Sciences, Poznan, Poland.
James D WestDivision of Allergy, Pulmonary and Critical Care Medicine, and.
David MontaniUniversité Paris-Saclay, Assistance Publique-Hôpitaux de Paris, Service de Pneumologie et Soins Intensifs Respiratoires, Hôpital de Bicêtre, DMU 5 Thorinno, Inserm UMR_S999, Le Kremlin-Bicêtre, France.ORCID 0000-0002-9358-6922
Mélanie EyriesSorbonne Université, AP-HP, Département de Génétique, Hôpital Pitié-Salpêtrière, Paris, France.
Mary P MullenDepartment of Cardiology, Boston Children's Hospital, Boston, Massachusetts.ORCID 0000-0002-0291-9630
Steven H AbmanPediatric Heart Lung Center, Department of Pediatrics and.ORCID 0000-0002-7292-2085
Matina PrapaSt. George's University Hospitals NHS Foundation Trust, London, United Kingdom.
Stefan GräfDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Heart and Lung Research Institute, Cambridge, United Kingdom.ORCID 0000-0002-1315-8873
Nicholas W MorrellDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Heart and Lung Research Institute, Cambridge, United Kingdom.
Anna R HemnesDivision of Allergy, Pulmonary and Critical Care Medicine, and.ORCID 0000-0002-2755-5845
Frédéric PerrosUniversité Paris-Saclay, Assistance Publique-Hôpitaux de Paris, Service de Pneumologie et Soins Intensifs Respiratoires, Hôpital de Bicêtre, DMU 5 Thorinno, Inserm UMR_S999, Le Kremlin-Bicêtre, France.ORCID 0000-0001-7730-2427
Rizwan HamidDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee.
Malcolm P O LoganRandall Centre for Cell and Molecular Biophysics, King's College London, London, United Kingdom.
Jeffrey WhitsettDivision of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Perinatal Institute, Cincinnati, Ohio.
Csaba GalambosDepartment of Pathology, University of Colorado School of Medicine, and Children's Hospital Colorado, Anschutz Medical Campus, Aurora, Colorado.
Paweł StankiewiczDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.ORCID 0000-0002-6456-7490
Wendy K ChungDepartment of Pediatrics and.
Eric D AustinDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee.ORCID 0000-0002-1709-9022
Inserm · FRPoznan University of Medical Sciences · PLPulmonary and Allergy Associates · USUniversity of Cambridge · GBVanderbilt University Medical Center · USBaylor College of Medicine · USBoston Children's Hospital · USChildren's Hospital Colorado · USCincinnati Children's Hospital Medical Center · USColumbia University Irving Medical Center · USKing's College London · GBLung Institute · USSorbonne Université · FRSt George’s University Hospitals NHS Foundation Trust · GB
Funding
Interventions Against the Molecular Etiology of BMPR2-induced PAHR01HL095797 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WEST, JAMES D · 2010 to 2022
$6.7MEstrogen signaling and energy metabolism in pulmonary arterial hypertensionR01HL134802 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI AUSTIN, ERIC DOUGLAS · 2018 to 2022
$3.7MMedical Research Council MR/S000038/1Medical Research Council MR/X000044/1NHLBI NIH HHS R01 HL095797NHLBI NIH HHS R01 HL134802
Abstract
Over the past decade, recognition of the profound impact of the
Indexed as
T-Box Domain ProteinsTranscription FactorsAnimalsHumansPhenotypeT-Box Domain ProteinsTBX4 protein, humanTranscription Factorslethal lung developmental disorderspulmonary arterial hypertensionTBX4 syndrome
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.