Evidence map›Paper›PMID 36367715›Full record

ArticleInternational endodontic journal2023

The use of electrodermal activity in pulpal diagnosis and dental pain assessment.

Hanh T Tran, Youngsun Kong, Ankur Talati, Hugo Posada-Quintero, Ki H Chon, I-Ping Chen

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International endodontic journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hanh T TranDepartment of Oral Health and Diagnostic Sciences, School of Dental Medicine, University of Connecticut Health, Farmington, Connecticut, USA.
Youngsun KongDepartment of Biomedical Engineering, School of Engineering, University of Connecticut, Storrs, Connecticut, USA.
Ankur TalatiDepartment of Oral Health and Diagnostic Sciences, School of Dental Medicine, University of Connecticut Health, Farmington, Connecticut, USA.
Hugo Posada-QuinteroDepartment of Biomedical Engineering, School of Engineering, University of Connecticut, Storrs, Connecticut, USA.ORCID https://orcid.org/0000-0003-4514-4772
Ki H ChonDepartment of Biomedical Engineering, School of Engineering, University of Connecticut, Storrs, Connecticut, USA.
I-Ping ChenDepartment of Oral Health and Diagnostic Sciences, School of Dental Medicine, University of Connecticut Health, Farmington, Connecticut, USA.ORCID https://orcid.org/0000-0002-7349-3091
UConn Health · USUniversity of Connecticut · US

Funding

Quantitative Assessment of Dental Pain using a smartphone-attachable electrodermal activity sensorR21DE029563 · NIDCR · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI CHEN, I-PING, CHON, KI H · 2020 to 2021
$463k
NIDCR NIH HHS R21 DE029563NIH HHS DE029563
6 · The paper itself

Abstract

aimsTo explore whether electrodermal activity (EDA) can serve as a complementary tool for pulpal diagnosis (Aim 1) and an objective metric to assess dental pain before and after local anaesthesia (Aim 2). METHODOLOGY: A total of 53 subjects (189 teeth) and 14 subjects (14 teeth) were recruited for Aim 1 and Aim 2, respectively. We recorded EDA using commercially available devices, PowerLab and Galvanic Skin Response (GSR) Amplifier, in conjunction with cold and electric pulp testing (EPT). Participants rated their level of sensation on a 0-10 visual analogue scale (VAS) after each test. We recorded EPT-stimulated EDA activity before and after the administration of local anaesthesia for participants who required root canal treatment (RCT) due to painful pulpitis. The raw data were converted to the time-varying index of sympathetic activity (TVSymp), a sensitive and specific parameter of EDA. Statistical analysis was performed using Python 3.6 and its Scikit-post hoc library.

resultsElectrodermal activity was upregulated by the stimuli of cold and EPT testing in the normal pulp. TVSymp signals were significantly increased in vital pulp compared to necrotic pulp by both cold test and EPT. Teeth that exhibited intensive sensitivity to cold with or without lingering pain had increased peak numbers of TVSymp than teeth with mild sensation to cold. Pre- and post-anaesthesia EDA activity and VAS scores were recorded in patients with painful pulpitis. Post-anaesthesia EDA signals were significantly lower compared to pre-anaesthesia levels. Approximately 71% of patients (10 of 14 patients) experienced no pain during treatment and reported VAS score of 0 or 1. The majority of patients (10 of 14) showed a reduction of TVSymp after the administration of anaesthesia. Two of three patients who experienced increased pain during RCT (post-treatment VAS > pre-treatment VAS) exhibited increased post-anaesthesia TVSymp.

conclusionsOur data show promising results for using EDA in pulpal diagnosis and for assessing dental pain. Whilst our testing was limited to subjects who had adequate communication skills, our future goal is to be able to use this technology to aid in the endodontic diagnosis of patients who have limited communication ability.

Indexed as

PulpitisDental PulpGalvanic Skin ResponseHumansPainPain Measurementelectrodermal activityendodonticspain assessmentpulpal diagnosis

Identifiers

PMID36367715
PMCPMC10044487
OpenAlexW4308766060

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.