Evidence map›Paper›PMID 36367478›Full record

ArticleACS applied materials & interfaces2022

Matrix Adhesiveness Regulates Myofibroblast Differentiation from Vocal Fold Fibroblasts in a Bio-orthogonally Cross-linked Hydrogel.

Jiyeon Song, Hanyuan Gao, He Zhang, Olivia J George, Ashlyn S Hillman, Joseph M Fox, Xinqiao Jia

Open access · greenAbstract read
In one paragraph

Article in ACS applied materials & interfaces, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jiyeon SongDepartment of Materials Science and Engineering, University of Delaware, Newark, Delaware 19716, United States.ORCID 0000-0003-1822-8006
Hanyuan GaoDepartment of Materials Science and Engineering, University of Delaware, Newark, Delaware 19716, United States.
He ZhangDepartment of Materials Science and Engineering, University of Delaware, Newark, Delaware 19716, United States.ORCID 0000-0003-1165-6702
Olivia J GeorgeDepartment of Materials Science and Engineering, University of Delaware, Newark, Delaware 19716, United States.
Ashlyn S HillmanDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, United States.
Joseph M FoxDepartment of Materials Science and Engineering, University of Delaware, Newark, Delaware 19716, United States.ORCID 0000-0002-8258-1640
Xinqiao JiaDepartment of Materials Science and Engineering, University of Delaware, Newark, Delaware 19716, United States.ORCID 0000-0002-3564-5576
University of Delaware · USBiotechnology Institute · US

Funding

Predictive Modeling & Optimal Control Framework for Model-Based Epidemic Response in DelawareP20GM103446 · NIGMS · UNIVERSITY OF DELAWARE · PI MELINDA K DUNCAN · 2012 to 2026
$67.2M
Understanding synovial macrophage inflamm-aging within osteoarthritisP20GM139760 · NIGMS · UNIVERSITY OF DELAWARE · PI DAWN M ELLIOTT · 2021 to 2026
$19.1M
A Hydrogel-Based Cellular Model of the Human Vocal FoldR01DC014461 · NIDCD · UNIVERSITY OF DELAWARE · PI Xinqiao Jia · 2016 to 2026
$6.2M
Research Supplements to Promote Diversity in Health-Related Research (Admin Supp)R01DE029655 · NIDCR · UNIVERSITY OF DELAWARE · PI Xinqiao Jia · 2021 to 2026
$2.8M
Zeiss LSM710 Inverted Confocal MicroscopeS10OD016361 · OD · UNIVERSITY OF DELAWARE · PI CAPLAN, JEFFREY L · 2015 to 2015
$444k
NIDCD NIH HHS R01 DC014461NIDCR NIH HHS R01 DE029655NIGMS NIH HHS P20 GM103446NIGMS NIH HHS P20 GM139760NIH HHS S10 OD016361
6 · The paper itself

Abstract

Repeated mechanical and chemical insults cause an irreversible alteration of extracellular matrix (ECM) composition and properties, giving rise to vocal fold scarring that is refractory to treatment. Although it is well known that fibroblast activation to myofibroblast is the key to the development of the pathology, the lack of a physiologically relevant

Indexed as

MyofibroblastsTransforming Growth Factor beta1AdhesivenessCicatrixFibroblastsHumansHydrogelsVocal CordsHydrogelsTransforming Growth Factor beta1cell-adhesive peptidemyofibroblaststetrazine ligationtransforming growth factor beta1vocal fold fibroblasts

Identifiers

PMID36367478
PMCPMC10350853
OpenAlexW4308770576

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.