Evidence map›Paper›PMID 36367459›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2023

Erythrose and Threose: Carbonyl Migrations, Epimerizations, Aldol, and Oxidative Fragmentation Reactions under Plausible Prebiotic Conditions.

Ruiqin Yi, Ryan Kern, Pamela Pollet, Huacan Lin, Ramanarayanan Krishnamurthy, Charles L Liotta

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ruiqin YiSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia, 30332, USA.ORCID http://orcid.org/0000-0003-2393-700X
Ryan KernSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia, 30332, USA.
Pamela PolletSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia, 30332, USA.
Huacan LinDepartment of Chemistry, The Scripps Research Institute, La Jolla, California, 92037, USA.
Ramanarayanan KrishnamurthyDepartment of Chemistry, The Scripps Research Institute, La Jolla, California, 92037, USA.
Charles L LiottaSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia, 30332, USA.ORCID http://orcid.org/0000-0002-7450-6640

Funding

Japan Society for the Promotion of Science (JSPS) Grant-in-aid 21K14029NASA Exobiology Program NNH20ZA001N- EXO Grant 20-EXO-0006National Science Foundation and the NASA Astrobiology Program under the Center for Chemical Evolution CHE-1504217the Astrobiology Center Program of National Institutes of Natural Sciences (NINS) AB031017
6 · The paper itself

Abstract

The prebiotic generation of sugars in the context of origins of life studies is of considerable interest. Among the important intramolecular processes of sugars are carbonyl migrations and accompanying epimerizations. Herein we describe the carbonyl migration-epimerization process occurring down the entire carbon chain of chirally pure d-tetroses sugars under mild conditions. Employing chirally pure 1-

Indexed as

aldol reactioncarbonyl migrationepimerizationformose reactiontetroses

Identifiers

PMID36367459
PMCPMC10107292

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.