ArticleThe Journal of physiology2023
Blood shifts between body compartments during submaximal exercise with induced expiratory flow limitation in healthy humans.
Article in The Journal of physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Geometric Analyses of the Expiratory Flow-Volume Curve to Identify Expiratory Flow Limitation During Exercise.Fluids (Basel, Switzerland) · 2025Article
- Assessing the repeatability of expiratory flow limitation during incremental exercise in healthy adults.Physiological reports · 2024Article
- Expiratory flow limitation during exercise: why does it 'suck' so much?The Journal of physiology · 2023Article
- Spirometric and exercise ventilatory predictors of expiratory flow-limitation in adults with normal and mildly-obstructed airways.Respiratory physiology & neurobiologyArticle
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
External expiratory flow limitation (EFLe) can be applied in healthy subjects to mimic the effects of chronic obstructive pulmonary disease during exercise. At maximal exercise intensity, EFLe leads to exercise intolerance owing to respiratory pump dysfunction limiting venous return. We quantified blood shifts between body compartments to determine whether such effects can be observed during submaximal exercise, when the load on the respiratory system is milder. Ten healthy men (25.2 ± 3.2 years of age, 177.3 ± 5.4 cm in height and weighing 67.4 ± 5.8 kg) exercised at 100 W (∼40% of maximal oxygen uptake) while breathing spontaneously (CTRL) or with EFLe. We measured respiratory dynamics with optoelectronic plethysmography, oesophageal (P
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