Evidence map›Paper›PMID 36367201›Full record

ArticleXenotransplantation2023

Xenotransplantation and exotransplantation: Strategies to expand the number of donor organs.

Daniel J Garry, Joshua I Weiner, Sarah M Greising, David H Sachs, Mary G Garry

Abstract read
In one paragraph

Article in Xenotransplantation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniel J GarryCardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0002-8970-7365
Joshua I WeinerDepartment of Surgery, Columbia Center for Translational Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Sarah M GreisingSchool of Kinesiology, University of Minnesota, Minneapolis, Minnesota, USA.
David H SachsDepartment of Surgery, Columbia Center for Translational Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Mary G GarryCardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0002-7958-5560

Funding

Bioengineering Strategies for Cardiovascular DiseaseR01HL144582 · NHLBI · UNIVERSITY OF MINNESOTA · PI GARRY, DANIEL J. · 2019 to 2022
$3.1M
NHLBI NIH HHS R01 HL144582
6 · The paper itself

Abstract

Cardiovascular disease is common and has a high mortality. Due to the limited number of organs available for orthotopic heart transplantation, alternative therapies have received intense interest. In this commentary we contrast xenotransplantation and blastocyst complementation to produce pigs that will serve as donors for organ transplantation. These strategies hold tremendous promise and have the potential to provide an unlimited number of organs for chronic, terminal diseases.

Indexed as

Heart TransplantationOrgan TransplantationTransplantsAnimalsHumansSwineTissue DonorsTransplantation, Heterologousblastocyst complementationETV2MYOD familyskeletal musclexenotransplantation

Identifiers

PMID36367201
PMCPMC13022990

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.