Evidence map›Paper›PMID 36367190›Full record

ArticleOncology reports2023

Loss of CD24 promotes radiation‑ and chemo‑resistance by inducing stemness properties associated with a hybrid E/M state in breast cancer cells.

Isaline Bontemps, Celine Lallemand, Denis Biard, Nathalie Dechamps, Thierry Kortulewski, Emmanuelle Bourneuf, Capucine Siberchicot, François Boussin, Sylvie Chevillard, Anna Campalans and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Oncology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

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  11. Re-Sensitizing Cancer Stem Cells to Conventional Chemotherapy Agents.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Isaline BontempsLaboratory of Experimental Cancerology, Institute of Cellular and Molecular Radiobiology, Genetic Stability Stem Cells and Radiation, François Jacob Institute of Biology, French Alternative Energies and Atomic Energy Commission (CEA), Paris University and Paris‑Saclay University, F‑92265 Fontenay‑aux‑Roses, France.
Celine LallemandLaboratory of Experimental Cancerology, Institute of Cellular and Molecular Radiobiology, Genetic Stability Stem Cells and Radiation, François Jacob Institute of Biology, French Alternative Energies and Atomic Energy Commission (CEA), Paris University and Paris‑Saclay University, F‑92265 Fontenay‑aux‑Roses, France.
Denis BiardUnit of Prion Disorders and Related Infectious Agents, François Jacob Institute of Biology, CEA, Paris‑Saclay University, F‑92265 Fontenay‑aux‑Roses, France.
Nathalie DechampsLaboratory of Radiopathology, Institute of Cellular and Molecular Radiobiology, Genetic Stability Stem Cells and Radiation, François Jacob Institute of Biology, CEA, French National Health and Medical Research Institute U1274, Paris University and Paris‑Saclay University, F‑92265 Fontenay‑aux‑Roses, France.
Thierry KortulewskiLaboratory of Radiopathology, Institute of Cellular and Molecular Radiobiology, Genetic Stability Stem Cells and Radiation, François Jacob Institute of Biology, CEA, French National Health and Medical Research Institute U1274, Paris University and Paris‑Saclay University, F‑92265 Fontenay‑aux‑Roses, France.
Emmanuelle BourneufLaboratory of Experimental Cancerology, Institute of Cellular and Molecular Radiobiology, Genetic Stability Stem Cells and Radiation, François Jacob Institute of Biology, French Alternative Energies and Atomic Energy Commission (CEA), Paris University and Paris‑Saclay University, F‑92265 Fontenay‑aux‑Roses, France.
Capucine SiberchicotLaboratory of Experimental Cancerology, Institute of Cellular and Molecular Radiobiology, Genetic Stability Stem Cells and Radiation, François Jacob Institute of Biology, French Alternative Energies and Atomic Energy Commission (CEA), Paris University and Paris‑Saclay University, F‑92265 Fontenay‑aux‑Roses, France.
François BoussinLaboratory of Radiopathology, Institute of Cellular and Molecular Radiobiology, Genetic Stability Stem Cells and Radiation, François Jacob Institute of Biology, CEA, French National Health and Medical Research Institute U1274, Paris University and Paris‑Saclay University, F‑92265 Fontenay‑aux‑Roses, France.
Sylvie ChevillardLaboratory of Experimental Cancerology, Institute of Cellular and Molecular Radiobiology, Genetic Stability Stem Cells and Radiation, François Jacob Institute of Biology, French Alternative Energies and Atomic Energy Commission (CEA), Paris University and Paris‑Saclay University, F‑92265 Fontenay‑aux‑Roses, France.
Anna CampalansLaboratory of Experimental Cancerology, Institute of Cellular and Molecular Radiobiology, Genetic Stability Stem Cells and Radiation, François Jacob Institute of Biology, French Alternative Energies and Atomic Energy Commission (CEA), Paris University and Paris‑Saclay University, F‑92265 Fontenay‑aux‑Roses, France.
Jerome LebeauLaboratory of Experimental Cancerology, Institute of Cellular and Molecular Radiobiology, Genetic Stability Stem Cells and Radiation, François Jacob Institute of Biology, French Alternative Energies and Atomic Energy Commission (CEA), Paris University and Paris‑Saclay University, F‑92265 Fontenay‑aux‑Roses, France.
Institut de Radiobiologie Cellulaire et Moléculaire · FRCEA Paris-Saclay · FRCommissariat à l'Énergie Atomique et aux Énergies Alternatives · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer stem cells (CSCs) serve an essential role in failure of conventional antitumor therapy. In breast cancer, CD24

Indexed as

CD24 AntigenNeoplasmsCell DifferentiationCell Line, TumorEpithelial-Mesenchymal TransitionHyaluronan ReceptorsNeoplastic Stem CellsReactive Oxygen SpeciesCD24 AntigenHyaluronan ReceptorsReactive Oxygen Speciesbreast cancercancer stem cellsCD24epithelial-mesenchymal transitionresistance

Identifiers

PMID36367190
PMCPMC9685273
OpenAlexW4308442719

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.