Evidence map›Paper›PMID 36367161›Full record

ArticleMolecular medicine reports2023

Wild‑type KRAS inhibits the migration and invasion of pancreatic cancer through the Wnt/β‑catenin pathway.

Xianhua Hu, Rendan Zhang, Jiaxin Yao, Bo Mu, Chunyan Zhao

Open access · hybridAbstract read
In one paragraph

Article in Molecular medicine reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xianhua HuDepartment of Medical Laboratory, North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China.
Rendan ZhangSchool of Basic Medicine and Forensic Medicine, North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China.
Jiaxin YaoSchool of Basic Medicine and Forensic Medicine, North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China.
Bo MuSchool of Basic Medicine and Forensic Medicine, North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China.
Chunyan ZhaoSichuan Key Laboratory of Medical Imaging, Institute of Medical Imaging, North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China.
North Sichuan Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kirsten rat sarcoma virus (KRAS) mutation is considered to be the event that leads to the initiation of pancreatic ductal adenocarcinoma (PDAC), the mutation frequency of the KRAS gene in PDAC is 90‑95%. Studies have shown that wild‑type KRAS (KRAS

Indexed as

Carcinoma, Pancreatic DuctalPancreatic NeoplasmsAnimalsbeta CateninKirsten murine sarcoma virusMiceMice, NudeMutationProto-Oncogene Proteins p21(ras)Wnt Signaling Pathwaybeta CateninProto-Oncogene Proteins p21(ras)mutant Kirsten rat sarcoma viruspancreatic cancerwild‑type Kirsten rat sarcoma virusWnt/β‑catenin

Identifiers

PMID36367161
PMCPMC9673065
OpenAlexW4308444665

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.