Evidence map›Paper›PMID 36367067›Full record

ArticleJournal of clinical neurology (Seoul, Korea)2022

AI-CoV Study: Autoimmune Encephalitis Associated With COVID-19 and Its Vaccines-A Systematic Review.

M M Samim, Debjyoti Dhar, Sheetal Goyal, Treshita Dey, Naznin Parvin, Rutul D Shah, Vikram Singh, Sampurna Chowdhury, Bhavesh Mohan Lal, Nibu Varghese and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of clinical neurology (Seoul, Korea), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Anti-LGI1 encephalitis in a COVID-19 patient with positive SARS-CoV-2 in CSF.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

M M SamimDepartment of Neurology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.ORCID https://orcid.org/0000-0002-3367-1455
Debjyoti DharDepartment of Neurology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India. deb.dhar.india@gmail.com.ORCID https://orcid.org/0000-0002-4835-4698
Sheetal GoyalDepartment of Neurology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.
Treshita DeyDepartment of Radiation Oncology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.ORCID https://orcid.org/0000-0001-7795-3596
Naznin ParvinDepartment of Pediatrics, Lady Hardinge Medical College and Hospital, New Delhi, India.ORCID https://orcid.org/0000-0002-7951-5183
Rutul D ShahDepartment of Neurology, Amrita Institute of Medical Sciences, Kochi, Kerala, India.ORCID https://orcid.org/0000-0002-4475-3413
Vikram SinghDepartment of Neurology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.ORCID https://orcid.org/0000-0003-4891-1404
Sampurna ChowdhuryDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.ORCID https://orcid.org/0000-0002-5010-7565
Bhavesh Mohan LalDepartment of General Medicine, All India Institute of Medical Sciences, New Delhi, India.ORCID https://orcid.org/0000-0001-5554-3342
Nibu VargheseDepartment of Neurology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.ORCID https://orcid.org/0000-0002-1818-2899
Abhishek GohelDepartment of Neurology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.ORCID https://orcid.org/0000-0002-7847-4551
Abhishek ChowdhuryDepartment of Neuropathology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.ORCID https://orcid.org/0000-0001-7948-6936
Aritra ChatterjeeCentre For Biosystems Science and Engineering, Indian Institute of Science, Bangalore, Karnataka, India.ORCID https://orcid.org/0000-0002-5318-3459
Shahyan SiddiquiConsultant Neuroradiologist, Department of Neuroimaging and Interventional Radiology, STAT Institute of Neurosciences, Hyderabad, India.ORCID https://orcid.org/0000-0002-8887-6546
National Institute of Mental Health and Neurosciences · INAll India Institute of Medical Sciences · INAmrita Institute of Medical Sciences and Research Centre · INCognitive Neuroimaging Lab · FRIndian Institute of Science Bangalore · INLady Hardinge Medical College · INPost Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeAutoimmune encephalitis (AIE) following coronavirus disease 2019 (COVID-19) is an underexplored condition. This study aims to systematically review the clinico-investigational and pathophysiologic aspects of COVID-19 and its vaccines in association with AIE, and identify the factors predicting neurological severity and outcomes.

methodsRelevant data sources were searched using appropriate search terms on January 15, 2022. Studies meeting the criteria for AIE having a temporal association with COVID-19 or its vaccines were included.

resultsOut of 1,894 citations, we included 61 articles comprising 88 cases: 71 of COVID-19-associated AIE, 3 of possible Bickerstaff encephalitis, and 14 of vaccine-associated AIE.There were 23 definite and 48 possible seronegative AIE cases. Anti-NMDAR (N-methyl-D-aspartate receptor;

conclusionsThe study has revealed diagnostic, therapeutic, and pathophysiological aspects of AIE associated with COVID-19 and its vaccines, and its differences from postinfectious AIE. SYSTEMATIC REVIEW REGISTRATION: PROSPERO registration number CRD42021299215.

Indexed as

autoimmune encephalitisCOVID-19COVID-19 vaccinepostinfectious encephalitis

Identifiers

PMID36367067
PMCPMC9669562
OpenAlexW4308770143

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.