Evidence map›Paper›PMID 36366958›Full record

ArticleJournal of the International Neuropsychological Society : JINS2023

Leisure activity engagement across adulthood predicts cognitive change after five years: Do gender and age matter?

Sharon Sanz Simon, Seonjoo Lee, Yian Gu, Ashley Mensing, Diala Noofoory, Geneva M Hidalgo Nazario, Reshma S Babukutty, Yaakov Stern

Open access · hybridAbstract read
In one paragraph

Article in Journal of the International Neuropsychological Society : JINS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  7. Cognitive resilience/reserve: Myth or reality? A review of definitions and measurement methods.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sharon Sanz SimonCognitive Neuroscience Division, Department of Neurology, Columbia University, New York, NY, USA.ORCID https://orcid.org/0000-0003-2603-6215
Seonjoo LeeDepartment of Psychiatry and Biostatistics, Columbia University, New York, NY, USA.
Yian GuCognitive Neuroscience Division, Department of Neurology, Columbia University, New York, NY, USA.ORCID https://orcid.org/0000-0002-4297-1548
Ashley MensingCognitive Neuroscience Division, Department of Neurology, Columbia University, New York, NY, USA.
Diala NoofooryCognitive Neuroscience Division, Department of Neurology, Columbia University, New York, NY, USA.
Geneva M Hidalgo NazarioCognitive Neuroscience Division, Department of Neurology, Columbia University, New York, NY, USA.
Reshma S BabukuttyCognitive Neuroscience Division, Department of Neurology, Columbia University, New York, NY, USA.
Yaakov SternCognitive Neuroscience Division, Department of Neurology, Columbia University, New York, NY, USA.
Columbia University · US

Funding

Research Education CoreP30AG066462 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Andrew Franklin Teich · 2020 to 2026
$30.1M
Exploring Cognitive Aging Using Reference Ability Neural NetworksR01AG038465 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HABECK, CHRISTIAN GEORG, STERN, YAAKOV · 2011 to 2025
$17.0M
Imaging of Cognition, Learning and Memory in AgingR01AG026158 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI STERN, YAAKOV · 2004 to 2021
$10.9M
Exploring Cognitive Aging Using Refernce Ability Neural NetworksRF1AG038465 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HABECK, CHRISTIAN GEORG, STERN, YAAKOV · 2016 to 2018
$7.6M
Diet and Cognition within a Reserve frameworkR01AG061008 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GU, YIAN · 2020 to 2024
$3.3M
NIA NIH HHS P30 AG066462NIA NIH HHS R01 AG026158NIA NIH HHS R01 AG038465NIA NIH HHS R01 AG061008NIA NIH HHS RF1 AG038465
6 · The paper itself

Abstract

objectiveTo examine the association between leisure activity (LA) frequency and cognitive trajectories over 5 years across adulthood, and whether gender and age moderate these associations.

methodA total of 234 cognitively healthy adults (21-80 years) completed a LA questionnaire at baseline and neuropsychological measures at baseline and after 5 years. Latent change score analysis was applied to generate latent variables estimating changes in different cognitive domains. For a secondary analysis, LA components' scores were calculated, reflecting cognitive-intellectual, social, and physical activities. Regression analysis examined the association between baseline LA and cognitive change, and potential moderation of gender and age. In addition, we tested the influence of cortical gray matter thickness on the results.

resultsWe found that higher LA engagement was associated with slower cognitive decline for reasoning, speed, and memory, as well as better vocabulary across two time points. Regarding LA components, higher Social-LA and Intellectual-LA predicted slower rates of cognitive decline across different domains, while Physical-LA was not associated with cognitive change. Gender, but not age, moderated some of the associations observed. Our results remained the same after controlling for cortical gray matter thickness.

conclusionsWe demonstrated a protective effect of LA engagement on cognitive trajectories over 5 years, independent from demographics and a measure of brain health. The effects were in part moderated by gender, but not age. Results should be replicated in larger and more diverse samples. Our findings support cognitive reserve hypothesis and have implications for future reserve-enhancing interventions.

Indexed as

Cognitive DysfunctionCognitive ReserveAdultBrainCognitionHumansLeisure Activitiesagingbrain thicknesscognitioncognitive reserveleisure activitylifespan

Identifiers

PMID36366958
PMCPMC10186268
OpenAlexW4308766524

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.