Evidence map›Paper›PMID 36366519›Full record

ArticleViruses2022

Molecular Characterization and Phylogenetic Analysis of Feline Calicivirus Isolated in Guangdong Province, China from 2018 to 2022.

Jianwei Mao, Shaotang Ye, Qi Li, Yumeizi Bai, Jieyan Wu, Liang Xu, Zhen Wang, Jingyu Wang, Pei Zhou, Shoujun Li

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jianwei MaoCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Shaotang YeCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Qi LiCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Yumeizi BaiCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Jieyan WuCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Liang XuCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Zhen WangCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Jingyu WangCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Pei ZhouCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.ORCID 0000-0003-2006-9163
Shoujun LiCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
South China Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Feline calicivirus (FCV) is a common feline infectious pathogen that mainly causes upper respiratory tract disease. To investigate the prevalence of FCV in Guangdong Province in China, a total of 152 nasal and throat swabs from cats suspected of FCV infection were collected in veterinary clinics or shelters from 2018 to 2022. The positive detection rate of FCV was 28.9% (44/152) by RT-PCR. In addition, twenty FCV isolates were successfully isolated and purified. Eleven out of twenty isolates were selected for further phylogenetic analyses based on the capsid protein VP1; our results revealed that seven isolates were in genogroup I, and four were in genogroup II. Notably, according to the whole genome phylogenetic tree, FCV-SCAU-11 was in the same branch as Korean isolates, and recombination analysis revealed that the FCV-SCAU-11 isolate showed potential recombinant events between the FCV-SH isolate and FCV-GXNN03-20 isolate. Furthermore, the virus replication kinetics indicated that FCV-SCAU-10, with clinically severe symptoms in patient cats, performed a more efficient replication in vitro. In conclusion, this study revealed the genetic diversity of FCVs in Guangdong Province, providing a reference for novel vaccine candidate strains and the development of effective strategies for preventing FCV infection in cats.

Indexed as

Caliciviridae InfectionsCalicivirus, FelineCat DiseasesAnimalsCapsid ProteinsCatsChinaPhylogenyCapsid Proteinsfeline calicivirusmutationphylogenetic analysisrecombinationvirulent systemic disease

Identifiers

PMID36366519
PMCPMC9696216
OpenAlexW4308119593

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.