Evidence map›Paper›PMID 36366456›Full record

ArticleViruses2022

Declining Prevalence of SARS-CoV-2 Antibodies among Vaccinated Nursing Home Residents and Staff Six Months after the Primary BNT162b2 Vaccination Campaign in Belgium: A Prospective Cohort Study.

Eline Meyers, Ellen Deschepper, Els Duysburgh, Liselore De Rop, Tine De Burghgraeve, Pauline Van Ngoc, Marina Digregorio, Simon Delogne, Anja Coen, Nele De Clercq and 7 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 2 countries.

Eline MeyersDepartment of Diagnostic Sciences, Faculty of Medicine and Health Sciences, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-3549-9548
Ellen DeschepperBiostatistics Unit, Faculty of Medicine and Health Sciences, Ghent University, 9000 Ghent, Belgium.
Els DuysburghDepartment of Epidemiology and Public Health, Sciensano, 1000 Brussels, Belgium.ORCID 0000-0003-3345-7616
Liselore De RopEPI-Centre, Department of Public Health and Primary Care, KU Leuven, 3000 Leuven, Belgium.
Tine De BurghgraeveEPI-Centre, Department of Public Health and Primary Care, KU Leuven, 3000 Leuven, Belgium.
Pauline Van NgocResearch Unit of Primary Care and Health, Department of General Medicine, Faculty of Medicine, University of Liège, 4000 Liège, Belgium.ORCID 0000-0003-0925-9994
Marina DigregorioResearch Unit of Primary Care and Health, Department of General Medicine, Faculty of Medicine, University of Liège, 4000 Liège, Belgium.ORCID 0000-0002-5317-7788
Simon DelogneResearch Unit of Primary Care and Health, Department of General Medicine, Faculty of Medicine, University of Liège, 4000 Liège, Belgium.
Anja CoenDepartment of Public Health and Primary Care, Faculty of Medicine and Health Sciences, Ghent University, 9000 Ghent, Belgium.
Nele De ClercqDepartment of Public Health and Primary Care, Faculty of Medicine and Health Sciences, Ghent University, 9000 Ghent, Belgium.
Laëtitia BuretResearch Unit of Primary Care and Health, Department of General Medicine, Faculty of Medicine, University of Liège, 4000 Liège, Belgium.
Samuel CoenenDepartment of Family Medicine & Population Health, Faculty of Medicine and Health Sciences, University of Antwerp, 2000 Antwerp, Belgium.ORCID 0000-0002-1238-8052
An De SutterDepartment of Public Health and Primary Care, Faculty of Medicine and Health Sciences, Ghent University, 9000 Ghent, Belgium.
Beatrice ScholtesResearch Unit of Primary Care and Health, Department of General Medicine, Faculty of Medicine, University of Liège, 4000 Liège, Belgium.ORCID 0000-0001-5274-822X
Jan Y VerbakelEPI-Centre, Department of Public Health and Primary Care, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-7166-7211
Piet CoolsDepartment of Diagnostic Sciences, Faculty of Medicine and Health Sciences, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0003-2980-5307
Stefan HeytensDepartment of Public Health and Primary Care, Faculty of Medicine and Health Sciences, Ghent University, 9000 Ghent, Belgium.
Ghent University · BEUniversity of Liège · BEKU Leuven · BESciensano (Belgium) · BEUniversity of Antwerp · BEUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the SCOPE study, we monitored SARS-CoV-2 antibodies in a national sample of residents and staff from Belgian nursing homes. Here, we report the seroprevalence among infected and infection-naive residents and staff after the primary COVID-19 vaccination campaign. Among 1554 vaccinated nursing home residents and 1082 vaccinated staff from 69 nursing homes in Belgium, we assessed the proportion having SARS-CoV-2 antibodies approximately two (April 2021), four (June 2021), and six months (August 2021) after a two-dose regimen of the BNT162b2 vaccine. We measured the seroprevalence using SARS-CoV-2 antibody rapid tests and collected socio-demographic and COVID-19 medical data using an online questionnaire. Two months after vaccination (baseline), we found a seroprevalence of 91% (95% CI: 89-93) among vaccinated residents and 99% (95% CI: 98-99) among vaccinated staff. Six months after vaccination, the seroprevalence significantly decreased to 68% (95% CI: 64-72) among residents and to 89% (95% CI; 86-91) among staff (

Indexed as

BNT162 VaccineCOVID-19Antibodies, ViralBelgiumCOVID-19 VaccinesHumansImmunization ProgramsNursing HomesPrevalenceProspective StudiesSARS-CoV-2Seroepidemiologic StudiesVaccinationAntibodies, ViralBNT162 VaccineCOVID-19 VaccinesBNT126b2COVID-19 vaccinationelderlyIgGIgMnursing home residentsSARS-CoV-2seroprevalence

Identifiers

PMID36366456
PMCPMC9696089
OpenAlexW4307306590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.