Evidence map›Paper›PMID 36366452›Full record

ArticleViruses2022

Application and Impact of Antiviral Therapy for Patients with HBV-Related Hepatocellular Carcinoma Receiving Sorafenib and Lenvatinib Treatment.

I-Cheng Lee, Pei-Chang Lee, Yee Chao, Chen-Ta Chi, Chi-Jung Wu, Yi-Ping Hung, Chien-Wei Su, Ming-Chih Hou, Yi-Hsiang Huang

Abstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

I-Cheng LeeDivision of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.ORCID 0000-0002-9316-4682
Pei-Chang LeeDivision of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Yee ChaoSchool of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.ORCID 0000-0001-5578-340X
Chen-Ta ChiDivision of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Chi-Jung WuDivision of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Yi-Ping HungSchool of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Chien-Wei SuDivision of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.ORCID 0000-0003-3889-7004
Ming-Chih HouDivision of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Yi-Hsiang HuangDivision of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.ORCID 0000-0001-5241-5425

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Overall survival (OS) in patients with advanced hepatocellular carcinoma (HCC) has improved in the era of multi-line sequential therapy. The application of antiviral therapy and its impact on survival for patients with HBV-related HCC needs to be reassessed. The aim of this study was to evaluate the application and impact of antiviral therapy on survival for patients with HBV-related HCC receiving tyrosine kinase inhibitor (TKI) therapy. Patients with advanced HBV-related HCC treated with sorafenib or lenvatinib as first-line therapy with (

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsAntiviral AgentsHepatitis B virusHumansPhenylurea CompoundsQuinolinesRetrospective StudiesSorafenibAntiviral AgentslenvatinibPhenylurea CompoundsQuinolinesSorafenibantiviral therapyentecavirhepatitis B virushepatocellular carcinomalenvatinibsorafenibtenofovirtyrosine kinase inhibitor

Identifiers

PMID36366452
PMCPMC9692815

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.