Evidence map›Paper›PMID 36366432›Full record

ArticleViruses2022

SARS-CoV-2 Seroprevalence among Canadian Blood Donors: The Advance of Omicron.

Sheila F O'Brien, Niamh Caffrey, Qi-Long Yi, Chantale Pambrun, Steven J Drews

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Canada's approach to SARS-CoV-2 sero-surveillance: Lessons learned for routine surveillance and future pandemics.Canadian journal of public health = Revue canadienne de sante publique · 2024
    Article
  4. Article
  5. Article
  6. SARS-CoV-2 seroprevalence in Nova Scotia blood donors.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2024
    Article
  7. Article
  8. The evolution of SARS-CoV-2 seroprevalence in Canada: a time-series study, 2020-2023.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Article
  9. Seroprevalence of Anti-SARS-CoV-2 Antibodies Following the Omicron BA.1 Wave.International journal of environmental research and public health · 2023
    Article
  10. An expanded role for blood donor emerging pathogens surveillance.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Sheila F O'BrienEpidemiology and Surveillance, Canadian Blood Services, Ottawa, ON K1G 4J5, Canada.
Niamh CaffreyEpidemiology and Surveillance, Canadian Blood Services, Ottawa, ON K1G 4J5, Canada.ORCID 0000-0003-3054-9144
Qi-Long YiEpidemiology and Surveillance, Canadian Blood Services, Ottawa, ON K1G 4J5, Canada.
Chantale PambrunMedical Affairs & Innovation, Canadian Blood Services, Ottawa, ON K1G 4J5, Canada.
Steven J DrewsMedical Microbiology, Canadian Blood Services, Edmonton, AB T6G 2R8, Canada.
University of Ottawa · CACanadian Blood Services · CAUniversity of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the emergence of the SARS-CoV-2 Omicron variant in late 2021, Canadian public health case/contact testing was scaled back due to high infection rates with milder symptoms in a highly vaccinated population. We monitored the seroprevalence of SARS-CoV-2 nucleocapsid (anti-N) and spike protein (anti-S) antibodies in blood donors across Canada from September 2021 to June 2022 in 202,123 randomly selected samples. Multivariable logistic regression of anti-N positivity with month, age, sex, racialization, region, material and social deprivation (based on postal code) identified as independent predictors. Piece-wise logistic regression analysed the association between anti-S concentration and month, and anti-N/anti-S positivity. Infection-related seroprevalence (anti-N positive) was 4.38% (95% CI: 3.96, 4.81) in September reaching 50.70% (50.15, 52.16) in June; nearly 100% were anti-S positive throughout. Anti-N positivity was associated with younger age, male sex, the Alberta and Prairies regions, greater material deprivation and less social deprivation (

Indexed as

COVID-19SARS-CoV-2AlbertaAntibodies, ViralBlood DonorsHumansMaleSeroepidemiologic StudiesAntibodies, Viralblood donorsCanadaOmicronSARS-CoV-2seroprevalence

Identifiers

PMID36366432
PMCPMC9695729
OpenAlexW4307548592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.