Evidence map›Paper›PMID 36366362›Full record

ArticleVaccines2022

Molecular Lipopolysaccharide Di-Vaccine Protects from Shiga-Toxin Producing Epidemic Strains of

Ivan A Dyatlov, Edward A Svetoch, Anna A Mironenko, Boris V Eruslanov, Victoria V Firstova, Nadezhda K Fursova, Alexander L Kovalchuk, Vyacheslav L Lvov, Petr G Aparin

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ivan A DyatlovState Research Center for Applied Microbiology and Biotechnology, Rospotrebnadzor, 142279 Obolensk, Moscow Region, Russia.
Edward A SvetochState Research Center for Applied Microbiology and Biotechnology, Rospotrebnadzor, 142279 Obolensk, Moscow Region, Russia.ORCID 0000-0002-3185-1954
Anna A MironenkoNational Research Center Institute of Immunology Federal Medical-Biology Agency (FMBA of Russia), 115522 Moscow, Russia.
Boris V EruslanovState Research Center for Applied Microbiology and Biotechnology, Rospotrebnadzor, 142279 Obolensk, Moscow Region, Russia.
Victoria V FirstovaState Research Center for Applied Microbiology and Biotechnology, Rospotrebnadzor, 142279 Obolensk, Moscow Region, Russia.
Nadezhda K FursovaState Research Center for Applied Microbiology and Biotechnology, Rospotrebnadzor, 142279 Obolensk, Moscow Region, Russia.ORCID 0000-0001-6053-2621
Alexander L KovalchukNational Research Center Institute of Immunology Federal Medical-Biology Agency (FMBA of Russia), 115522 Moscow, Russia.ORCID 0000-0003-2761-0442
Vyacheslav L LvovNational Research Center Institute of Immunology Federal Medical-Biology Agency (FMBA of Russia), 115522 Moscow, Russia.
Petr G AparinNational Research Center Institute of Immunology Federal Medical-Biology Agency (FMBA of Russia), 115522 Moscow, Russia.
State Research Center for Applied Microbiology and Biotechnology · RUFederal Medical-Biological Agency · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundShiga toxin-producing

methodsthe native

resultsintraperitoneal immunization of BALB/c mice with Ac

conclusionsDi-vaccine induced both systemic and intestinal anti-colonization immunity in mice simultaneously against two highly virulent human STEC strains. The possibility of creating a multivalent STEC vaccine based on safe Ac

Indexed as

antibody responseclinically applicable LPSintragastric infectionintraperitoneal infectionSTEC

Identifiers

PMID36366362
PMCPMC9692684
OpenAlexW4307988536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.