Evidence map›Paper›PMID 36366356›Full record

ArticleVaccines2022

Effect of Lockdowns on Hospital Staff in a COVID Center: A Retrospective Observational Study.

Giuseppe Vetrugno, Maurizio Sanguinetti, Rita Murri, Michela Sali, Simona Marchetti, Rosaria Santangelo, Massimo Fantoni, Antonella Cingolani, Giancarlo Scoppettuolo, Michele Di Donato and 17 more

Abstract read
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Giuseppe VetrugnoFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.
Maurizio SanguinettiFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.
Rita MurriFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0001-9468-5458
Michela SaliFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.
Simona MarchettiFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.
Rosaria SantangeloFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.
Massimo FantoniFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0001-6913-8460
Antonella CingolaniFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0002-3793-2755
Giancarlo ScoppettuoloFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.
Michele Di DonatoFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.
Vincenzo M GrassiFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.
Federica FotiFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.
Luca MarcheseFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.
Fabio De-GiorgioFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.
Antonio OlivaFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0001-7112-9096
Domenico StaitiFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.
Francesco Maria De SimoneFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.
Domenico PascucciFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0002-5804-2284
Fidelia CasciniFaculty of Medicine and Surgery, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0001-6499-0734
Roberta PastorinoFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.
Denise Pires-MarafonFaculty of Medicine and Surgery, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Andrea CambieriFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.
Patrizia LaurentiFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0002-8532-0593
Stefania BocciaFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0002-1864-749X
Walter RicciardiFaculty of Medicine and Surgery, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0002-5655-688X
Francesco FranceschiFondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.
On Behalf Of Gemelli-Against-Covid

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

At the onset of the SARS-CoV-2 pandemic, individual and social measures were strengthened through restrictive non-pharmaceutical interventions, labelled with the term “lockdown”. In Italy, there were two lockdowns (9 March 2020−3 May 2020 and 3 November 2020−27 March 2021). As part of preventive measures, healthcare workers and the administrative staff population of Policlinico A. Gemelli underwent nasopharyngeal swab tests from 1 March 2020 to 9 February 2022, a long time interval that includes the two aforementioned lockdowns. The population included 8958 people from 1 March 2020 to 31 December 2020; 8981 people from 1 January 2021 to 31 December 2021; and 8981 people from 1 January 2022 to 9 February 2022. We then analysed pseudo-anonymized data, using a retrospective observational approach to evaluate the impact of the lockdown on the incidence of SARS-CoV-2 infections within the population. Given the 14 day contagious period, the swab positivity rate (SPR) among the staff decreased significantly at the end of the first lockdown, every day prior to 18 May 2020, by 0.093 (p < 0.0001, CI = (−0.138−−0.047)). After the fourteenth day post the end of the first lockdown (18 May 2020), the SPR increased daily at a rate of 0.024 (p < 0.0001, 95% CI = (0.013−0.034)). In addition, the SPR appeared to increase significantly every day prior to 17 November 2020 by 0.024 (p < 0.0001, CI = (0.013−0.034)). After the fourteenth day post the start of the second lockdown (17 November 2020), the SPR decreased daily at a rate of 0.039 (p < 0.0001, 95% CI = (−0.050−−0.027)). These data demonstrate that, in our Institution, the lockdowns helped to both protect healthcare workers and maintain adequate standards of care for COVID and non-COVID patients for the duration of the state of emergency in Italy.

Indexed as

COVID-19healthcare workerslockdownswabvaccination

Identifiers

PMID36366356
PMCPMC9698425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.