Evidence map›Paper›PMID 36365608›Full record

ArticlePolymers2022

Gelation and the Self-Healing Behavior of the Chitosan-Catechol Hydrogel.

Yu-Ting Lan, Qian-Pu Cheng, Junpeng Xu, Shih-Ho Lin, Jhih-Min Lin, Shan-Hui Hsu

Abstract read
In one paragraph

Article in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yu-Ting LanInstitute of Polymer Science and Engineering, National Taiwan University, Taipei 10617, Taiwan.
Qian-Pu ChengInstitute of Polymer Science and Engineering, National Taiwan University, Taipei 10617, Taiwan.
Junpeng XuInstitute of Polymer Science and Engineering, National Taiwan University, Taipei 10617, Taiwan.ORCID 0000-0001-6106-441X
Shih-Ho LinInstitute of Polymer Science and Engineering, National Taiwan University, Taipei 10617, Taiwan.
Jhih-Min LinNational Synchrotron Radiation Research Center, Hsinchu 30076, Taiwan.
Shan-Hui HsuInstitute of Polymer Science and Engineering, National Taiwan University, Taipei 10617, Taiwan.ORCID 0000-0003-3399-055X

Funding

National Science and Technology Council, Taiwan, R.O.C. NSTC 108-2221-E-002-082-MY3National Synchrotron Radiation Research Center (NSRRC), Taiwan, R.O.C. 2020-3-083-3
6 · The paper itself

Abstract

Mussel-inspired adhesive hydrogels have been developed in biomedical fields due to their strong adhesive property, cohesive capability, biocompatibility, and hemostatic ability. Catechol-functionalized chitosan is a potential polymer used to prepare adhesive hydrogels. However, the unique gelation mechanism and self-healing properties of catechol-grafted chitosan alone have not yet been explored. Herein, catechol-grafted chitosan (CC) was synthesized and further concentrated to obtain the self-healing CC hydrogels. The gelation mechanism of CC hydrogels may be attributed to the formation of hydrogen bonding, cation-π interactions, Michael addition, or Schiff base reactions during concentration phases. Rheological studies showed that the CC hydrogel owned self-healing properties in repeated damage-healing cycles. Coherent small-angle X-ray scattering (SAXS) analyses revealed the formation of a mesoscale structure (~9 nm) as the solid content of the hydrogel increased. In situ SAXS combined with rheometry verified the strain-dependent behavior of the CC hydrogel. The CC hydrogel displayed the osmotic-responsive behavior and enhanced adhesive strength (0.38 N/cm

Indexed as

adhesivechitosan–catecholgelationnetwork structurescaffoldself-healing hydrogel

Identifiers

PMID36365608
PMCPMC9653763

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.