Evidence map›Paper›PMID 36365285›Full record

ArticlePlants (Basel, Switzerland)2022

Chemical and Biological Activity Profiling of Hedyosmum strigosum Todzia Essential Oil, an Aromatic Native Shrub from Southern Ecuador

Luis Cartuche, James Calva, Eduardo Valarezo, Nayeli Chuchuca, Vladimir Morocho

Open access · goldAbstract read
In one paragraph

Article in Plants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Molecules (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Review
  6. Food science and biotechnology · 2024
    Review
  7. Chemical Profiling ofPlants (Basel, Switzerland) · 2024
    Article
  8. Article
  9. Plant Essential Oil with Biological Activity (II).Plants (Basel, Switzerland) · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Luis CartucheDepartamento de Química y Ciencias Exactas, Universidad Técnica Particular de Loja (UTPL), Calle M.Champagnat s/n, Loja 1101608, Ecuador.ORCID 0000-0001-7227-4092
James CalvaDepartamento de Química y Ciencias Exactas, Universidad Técnica Particular de Loja (UTPL), Calle M.Champagnat s/n, Loja 1101608, Ecuador.ORCID 0000-0003-0608-8990
Eduardo ValarezoDepartamento de Química y Ciencias Exactas, Universidad Técnica Particular de Loja (UTPL), Calle M.Champagnat s/n, Loja 1101608, Ecuador.ORCID 0000-0001-9958-5042
Nayeli ChuchucaDepartamento de Química y Ciencias Exactas, Universidad Técnica Particular de Loja (UTPL), Calle M.Champagnat s/n, Loja 1101608, Ecuador.
Vladimir MorochoDepartamento de Química y Ciencias Exactas, Universidad Técnica Particular de Loja (UTPL), Calle M.Champagnat s/n, Loja 1101608, Ecuador.ORCID 0000-0001-5156-0700
Universidad Técnica Particular de Loja · EC

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to determine the chemical composition, enantiomeric distribution and the biological profile of Hedyosmum strigosum essential oil (EO). The antioxidant properties and anticholinesterase effect were measured by spectroscopic methods and antimicrobial potency assessed against 8 bacteria and two fungi. H. strigosum is a native shrub, particularly found in Ecuador and Colombia at 2000 to 3500 m a.s.l. Chemical composition was determined by GC-MS and GC-FID. A total of 44 compounds were detected, representing more than 92% of the EO composition. The main compounds were thymol (24.35, 22.48%), α-phellandrene (12.15, 13.93%), thymol acetate (6.59, 9.39%) and linalool (8.73, 5.82%), accounting for more than 51% of the EO. The enantioselective analysis revealed the presence of 5 pure enantiomers and 3 more as a racemic mixture. The EO exerted a strong antioxidant capacity, determined by ABTS assay, with a SC50 of 25.53 µg/mL and a strong and specific antimicrobial effect against Campylobacter jejuni with a MIC value of 125 µg/mL. A moderate acetylcholinesterase inhibitory effect was also observed with an IC50 value of 137.6 µg/mL. To the best of our knowledge this is the first report of the chemical composition and biological profile of H. strigosum EO.

Indexed as

acetylcholinesterasechemical profilingenantiomeric distributionessential oilthymolα-pineneα-thujene

Identifiers

PMID36365285
PMCPMC9655585
OpenAlexW4307551994

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.