Evidence map›Paper›PMID 36365227›Full record

ArticlePharmaceutics2022

DNA Binding and Anticancer Properties of New Pd(II)-Phosphorus Schiff Base Metal Complexes.

Burcu Saygıdeğer Demir, Simay İnce, Mustafa Kemal Yilmaz, Aycan Sezan, Ezgi Derinöz, Tugba Taskin-Tok, Yasemin Saygideger

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Burcu Saygıdeğer DemirDepartment of Biotechnology, Institute of Natural and Applied Sciences, Çukurova University, Adana 01330, Turkey.ORCID 0000-0001-5179-0522
Simay İnceDepartment of Nanotechnology and Advanced Materials, Institute of Science and Technology, Mersin University, Mersin 33343, Turkey.ORCID 0000-0002-9941-7281
Mustafa Kemal YilmazDepartment of Nanotechnology and Advanced Materials, Institute of Science and Technology, Mersin University, Mersin 33343, Turkey.ORCID 0000-0002-9969-3956
Aycan SezanDepartment of Biotechnology, Institute of Natural and Applied Sciences, Çukurova University, Adana 01330, Turkey.
Ezgi DerinözDepartment of Biotechnology, Institute of Natural and Applied Sciences, Çukurova University, Adana 01330, Turkey.
Tugba Taskin-TokDepartment of Chemistry, Faculty of Arts and Science, Gaziantep University, Gaziantep 27410, Turkey.ORCID 0000-0002-0064-8400
Yasemin SaygidegerDepartment of Biotechnology, Institute of Natural and Applied Sciences, Çukurova University, Adana 01330, Turkey.ORCID 0000-0003-3293-373X
Cukurova University · TRMersin Üniversitesi · TRGaziantep University · TR

Funding

Cukurova University Scientific Research Council CU-BAP-2022-1550
6 · The paper itself

Abstract

DNA has become the target of metal complexes in cancer drug discovery. Due to the side effects of widely known cisplatin and its derivative compounds, alternative metal-based drug discovery studies are still ongoing. In this study, the DNA-binding ability of Pd(II) and Pt(II) complexes of four phosphorus Schiff base ligands and four hydrazonoic-phosphines are investigated by using in silico analyses. Phosphorus Schiff base-Pd(II) complexes encoded as

Indexed as

antitumorapoptosiscancer cellscytotoxicityDNA bindingmetal complexesmolecular dockingphosphorus Schiff base

Identifiers

PMID36365227
PMCPMC9697782
OpenAlexW4308506799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.