Evidence map›Paper›PMID 36365178›Full record

ArticlePharmaceutics2022

Peelable Nanocomposite Coatings: "Eco-Friendly" Tools for the Safe Removal of Radiopharmaceutical Spills or Accidental Contamination of Surfaces in General-Purpose Radioisotope Laboratories.

Traian Rotariu, Daniela Pulpea, Gabriela Toader, Edina Rusen, Aurel Diacon, Valentina Neculae, John Liggat

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Traian RotariuMilitary Technical Academy "Ferdinand I", 39-49 George Cosbuc Boulevard, 050141 Bucharest, Romania.
Daniela PulpeaMilitary Technical Academy "Ferdinand I", 39-49 George Cosbuc Boulevard, 050141 Bucharest, Romania.
Gabriela ToaderMilitary Technical Academy "Ferdinand I", 39-49 George Cosbuc Boulevard, 050141 Bucharest, Romania.ORCID 0000-0003-2647-9331
Edina RusenFaculty of Chemical Engineering and Biotechnologies, University 'POLITEHNICA' of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania.ORCID 0000-0002-1660-017X
Aurel DiaconMilitary Technical Academy "Ferdinand I", 39-49 George Cosbuc Boulevard, 050141 Bucharest, Romania.ORCID 0000-0001-5171-2049
Valentina NeculaeInstitute for Nuclear Research-RATEN ICN-Pitesti, 1 Street Campului, 115400 Mioveni, Romania.ORCID 0000-0003-2657-4603
John LiggatDepartment of Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow G1 1BX, UK.
Military Technical Academy · ROInstitute for Nuclear Research Pitesti · ROUniversitatea Națională de Știință și Tehnologie Politehnica București · ROUniversity of Strathclyde · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radioactive materials are potentially harmful due to the radiation emitted by radionuclides and the risk of radioactive contamination. Despite strict compliance with safety protocols, contamination with radioactive materials is still possible. This paper describes innovative and inexpensive formulations that can be employed as 'eco-friendly' tools for the safe decontamination of radiopharmaceuticals spills or other accidental radioactive contamination of the surfaces arising from general-purpose radioisotope handling facilities (radiopharmaceutical laboratories, hospitals, research laboratories, etc.). These new peelable nanocomposite coatings are obtained from water-based, non-toxic, polymeric blends containing readily biodegradable components, which do not damage the substrate on which they are applied while also displaying efficient binding and removal of the contaminants from the targeted surfaces. The properties of the film-forming decontamination solutions were assessed using rheological measurements and evaporation rate tests, while the resulting strippable coatings were subjected to Fourier-transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), differential scanning calorimetry (DSC), and tensile tests. Radionuclide decontamination tests were performed on various types of surfaces encountered in radioisotope workspaces (concrete, painted metal, ceramic tiles, linoleum, epoxy resin cover). Thus, it was shown that they possess remarkable properties (thermal and mechanical resistance which permits facile removal through peeling) and that their capacity to entrap and remove beta and alpha particle emitters depends on the constituents of the decontaminating formulation, but more importantly, on the type of surface tested. Except for the cement surface (which was particularly porous), at which the decontamination level ranged between approximately 44% and 89%, for all the other investigated surfaces, a decontamination efficiency ranging from 80.6% to 96.5% was achieved.

Indexed as

accidental contaminationdecontaminationnanocomposite coatingpeelable/strippable filmsradioisotope laboratoryradionuclidesradiopharmaceutical spill

Identifiers

PMID36365178
PMCPMC9695050
OpenAlexW4307922029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.