Evidence map›Paper›PMID 36365148›Full record

ArticlePharmaceutics2022

Epidemiology of Treated Diabetes Ocular Complications in France 2008-2018-The LANDSCAPE French Nationwide Study.

Catherine Creuzot-Garcher, Pascale Massin, Mayer Srour, Florian Baudin, Corinne Dot, Sylvia Nghiem-Buffet, Jean-Francois Girmens, Cedric Collin, Anne Ponthieux, Cecile Delcourt

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 1 country.

Catherine Creuzot-GarcherDepartment of Ophthalmology, University Hospital, 21000 Dijon, France.
Pascale MassinCabinet d'Ophtalmologie de Breteuil, Centre Broca, Hôpital Lariboisière, 75013 Paris, France.
Mayer SrourDepartment of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, Université de Paris Est Créteil, 94000 Créteil, France.
Florian BaudinDepartment of Ophthalmology, University Hospital, 21000 Dijon, France.ORCID 0000-0003-4976-9876
Corinne DotDepartment of Ophthalmology, Desgenettes Military Hospital, 69003 Lyon, France.ORCID 0000-0003-4398-3978
Sylvia Nghiem-BuffetCentre d'Imagerie et de Laser, 75015 Paris, France.
Jean-Francois GirmensDepartment of Ophthalmology, INSERM-DGOS CIC 1423, Centre Hospitalier National d'Ophtalmologie (CHNO) des Quinze-Vingts, 75012 Paris, France.ORCID 0000-0002-9102-8716
Cedric CollinIQVIA France, 92099 La Défense, France.
Anne PonthieuxNovartis Pharma SAS, 8/10 rue Henri Sainte Claire Deville, 92563 Rueil-Malmaison, France.
Cecile DelcourtTeam LEHA, Bordeaux Population Health Research Center, UMR 1219, Institut National de la Santé et de la Recherche Médicale (Inserm), University of Bordeaux, 33000 Bordeaux, France.ORCID 0000-0002-2099-0481
CHU Dijon Bourgogne · FRCentre Ophtalmologique d'Imagerie et de Laser · FRHôpital Broca · FRHôpital d'instruction des Armées Desgenettes · FRInserm · FRIQVIA (France) · FRNovartis (France) · FRUniversité de Bordeaux · FRUniversité Paris-Est Créteil · FR

Funding

Novartis Pharma S.A.S. NA
6 · The paper itself

Abstract

aimLANDSCAPE aimed to estimate the annual incidence and prevalence of treated diabetic macular edema (DME) and proliferative diabetic retinopathy (PDR) between 2008 and 2018.

methodsThis French nationwide observational study used data from the French National Health Insurance Databases covering 99% of the French population. Data about healthcare consumption were used to identify adults treated with anti-VEGFs or dexamethasone implants (for DME) and with pan-retinal photocoagulation (for PDR). All French patients newly treated between 2008 and 2018 were included. Incidence and prevalence of treated DME and PDR were estimated for the age-matched general population and the population with diabetes in France. Sociodemographic characteristics and medical history were described in both populations.

resultsWe identified 53,584 treated DME patients and 127,273 treated PDR patients between 2008 and 2018, and 11,901 DME and 11,996 PDR new incident patients in 2018. The treated DME incidence in 2018 was 2.5 per 10,000 in the general population and 37.3 per 10,000 in the population with diabetes. Prevalence in 2018 was 9.5 and 143.7 per 10,000 in the respective populations. Treated PDR incidence in 2018 was 2.3 per 10,000 in the general population and 31.2 per 10,000 in the population with diabetes. Prevalence in 2018 was 19.9 and 270.3 per 10,000 in the respective populations. Incidence and prevalence were not age-dependent. Incidence of treated PDR incidence was relatively stable from 2008-2018. Incidence of treated DME incidence rose from 2012-2018, probably due to widening access to newly available treatments, such as anti-VEGFs.

conclusionsWe provide exhaustive nationwide data on the incidence and prevalence of treated diabetic ocular complications in France over a 10-year period.

Indexed as

diabetic macular edemadiabetic retinopathydrug consumptionFranceincidencenationwide studyprevalence

Identifiers

PMID36365148
PMCPMC9697089
OpenAlexW4307943429

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.